| Literature DB >> 20005831 |
Steven E Artandi1, Julia Promisel Cooper.
Abstract
The linearity of eukaryotic chromosomes presents challenges to cells, as the presence of DNA "ends" poses problems for the DNA replication machinery and the cell's damage response systems. This year's Nobel Prize in Physiology or Medicine recognized groundbreaking studies establishing the telomere field as a crucial area of biomedical research.Mesh：
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Year: 2009 PMID： 20005831 DOI： 10.1016/j.molcel.2009.11.030
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970