| Literature DB >> 21546286 |
Nadia Solovieff1, Stephen W Hartley, Clinton T Baldwin, Elizabeth S Klings, Mark T Gladwin, James G Taylor, Gregory J Kato, Lindsay A Farrer, Martin H Steinberg, Paola Sebastiani.
Abstract
The inheritance of genetic disease depends on ancestry that must be considered when interpreting genetic association studies and can provide insights when comparing traits in a population. We compared the genetic profiles of African Americans with sickle cell disease to those of Black Africans and Caucasian populations of European descent and found that they are less genetically admixed than other African Americans and have an ancestry similar to Yorubans, Mandenkas and Bantu.Entities:
Mesh:
Year: 2011 PMID: 21546286 PMCID: PMC3116635 DOI: 10.1016/j.bcmd.2011.04.002
Source DB: PubMed Journal: Blood Cells Mol Dis ISSN: 1079-9796 Impact factor: 3.039