| Literature DB >> 21527910 |
Abstract
Chromatin is the ensemble of genomic DNA and a large number of proteins. Various genome-wide mapping techniques have begun to reveal that, despite the tremendous complexity, chromatin organization is governed by simple principles. This review discusses the principles that drive the spatial architecture of chromatin, as well as genome-wide-binding patterns of chromatin proteins.Mesh:
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Year: 2011 PMID: 21527910 PMCID: PMC3098493 DOI: 10.1038/emboj.2011.135
Source DB: PubMed Journal: EMBO J ISSN: 0261-4189 Impact factor: 11.598