| Literature DB >> 21526968 |
Richard Sayre1, John R Beeching, Edgar B Cahoon, Chiedozie Egesi, Claude Fauquet, John Fellman, Martin Fregene, Wilhelm Gruissem, Sally Mallowa, Mark Manary, Bussie Maziya-Dixon, Ada Mbanaso, Daniel P Schachtman, Dimuth Siritunga, Nigel Taylor, Herve Vanderschuren, Peng Zhang.
Abstract
More than 250 million Africans rely on the starchy root crop cassava (Manihot esculenta) as their staple source of calories. A typical cassava-based diet, however, provides less than 30% of the minimum daily requirement for protein and only 10%-20% of that for iron, zinc, and vitamin A. The BioCassava Plus (BC+) program has employed modern biotechnologies intended to improve the health of Africans through the development and delivery of genetically engineered cassava with increased nutrient (zinc, iron, protein, and vitamin A) levels. Additional traits addressed by BioCassava Plus include increased shelf life, reductions in toxic cyanogenic glycosides to safe levels, and resistance to viral disease. The program also provides incentives for the adoption of biofortified cassava. Proof of concept was achieved for each of the target traits. Results from field trials in Puerto Rico, the first confined field trials in Nigeria to use genetically engineered organisms, and ex ante impact analyses support the efficacy of using transgenic strategies for the biofortification of cassava.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21526968 DOI： 10.1146/annurev-arplant-042110-103751
Source DB: PubMed Journal: Annu Rev Plant Biol ISSN： 1543-5008 Impact factor: 26.379