Literature DB >> 21508162

Identification of false-positive syphilis antibody results using a semiquantitative algorithm.

Belinda Yen-Lieberman1, Juliet Daniel, Cathy Means, Joan Waletzky, Thomas M Daly.   

Abstract

Screening patients for syphilis serology using a "treponemal assay-first" approach presents unique challenges, particularly when applied to low-prevalence populations. The use of a screening algorithm that incorporates semiquantitative values from treponemal antibody test results can help to identify potential false-positive results while requiring a minimum of repeat testing.

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Year:  2011        PMID： 21508162      PMCID： PMC3122602          DOI： 10.1128/CVI.05066-11

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  11 in total

1.  The laboratory impact of changing syphilis screening from the rapid-plasma reagin to a treponemal enzyme immunoassay: a case-study from the Greater Toronto Area.

Authors:  Sharmistha Mishra; Marie-Claude Boily; Victoria Ng; Wayne L Gold; Tom Okura; Marsha Shaw; Tony Mazzulli; David N Fisman
Journal:  Sex Transm Dis       Date:  2011-03       Impact factor: 2.830

2.  The tale of two serologic tests to screen for syphilis--treponemal and nontreponemal: does the order matter?

Authors:  Kwame Owusu-Edusei; Kathryn A Koski; Ronald C Ballard
Journal:  Sex Transm Dis       Date:  2011-05       Impact factor: 2.830

3.  Cost effectiveness of enzyme immunoassay and immunoblot testing for the diagnosis of syphilis.

Authors:  Anderson Chuck; Arto Ohinmaa; Peter Tilley; Ameeta Singh; Philip Jacobs
Journal:  Int J STD AIDS       Date:  2008-06       Impact factor: 1.359

4.  Discordant results from reverse sequence syphilis screening--five laboratories, United States, 2006-2010.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2011-02-11       Impact factor: 17.586

5.  Evaluation of an IgM/IgG sensitive enzyme immunoassay and the utility of index values for the screening of syphilis infection in a high-risk population.

Authors:  Ernest H Wong; Jeffrey D Klausner; Gloria Caguin-Grygiel; Carmela Madayag; Kim O Barber; Julia S Qiu; Sally Liska; Mark W Pandori
Journal:  Sex Transm Dis       Date:  2011-06       Impact factor: 2.830

6.  Treponema-specific tests for serodiagnosis of syphilis: comparative evaluation of seven assays.

Authors:  M J Binnicker; D J Jespersen; L O Rollins
Journal:  J Clin Microbiol       Date:  2011-02-23       Impact factor: 5.948

7.  Evaluation of the Bio-Rad BioPlex 2200 syphilis multiplex flow immunoassay for the detection of IgM- and IgG-class antitreponemal antibodies.

Authors:  E Gomez; D J Jespersen; J A Harring; M J Binnicker
Journal:  Clin Vaccine Immunol       Date:  2010-04-28

8.  Syphilis testing algorithms using treponemal tests for initial screening--four laboratories, New York City, 2005-2006.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2008-08-15       Impact factor: 17.586

9.  Evaluation of the LIAISON chemiluminescence immunoassay for diagnosis of syphilis.

Authors:  Carrie S Knight; Mary A Crum; Robert W Hardy
Journal:  Clin Vaccine Immunol       Date:  2007-04-25

10.  Comparative evaluation of 15 serological assays for the detection of syphilis infection.

Authors:  M J Cole; K R Perry; J V Parry
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2007-10       Impact factor: 3.267
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  6 in total

1.  It is time to use treponema-specific antibody screening tests for diagnosis of syphilis.

Authors:  Michael J Loeffelholz; Matthew J Binnicker
Journal:  J Clin Microbiol       Date:  2011-11-16       Impact factor: 5.948

2.  Analysis of bioplex syphilis IgG quantitative results in different patient populations.

Authors:  Michael J Loeffelholz; Tony Wen; Janak A Patel
Journal:  Clin Vaccine Immunol       Date:  2011-08-31

3.  Correlation of Treponemal Immunoassay Signal Strength Values with Reactivity of Confirmatory Treponemal Testing.

Authors:  Yetunde F Fakile; Heather Jost; Karen W Hoover; Kathleen J Gustafson; Susan M Novak-Weekley; Jeff M Schapiro; Anthony Tran; Joan M Chow; Ina U Park
Journal:  J Clin Microbiol       Date:  2017-12-26       Impact factor: 5.948

4.  Analytical Comparison of the Architect Syphilis TP and Liaison Treponema Automated Chemiluminescent Immunoassays and Their Performance in a Reverse Syphilis Screening Algorithm.

Authors:  Alan M Sanfilippo; Kristie Freeman; John L Schmitz
Journal:  J Clin Microbiol       Date:  2018-07-26       Impact factor: 5.948

5.  Evaluation of the BioPlex 2200 syphilis system as a first-line method of reverse-sequence screening for syphilis diagnosis.

Authors:  Antonella Marangoni; Paola Nardini; Claudio Foschi; Alessandra Moroni; Antonietta D'Antuono; Letizia Bacchi Reggiani; Roberto Cevenini
Journal:  Clin Vaccine Immunol       Date:  2013-05-22

6.  The Traditional or Reverse Algorithm for Diagnosis of Syphilis: Pros and Cons.

Authors:  Daniel A Ortiz; Mayur R Shukla; Michael J Loeffelholz
Journal:  Clin Infect Dis       Date:  2020-06-24       Impact factor: 9.079
  6 in total

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