Literature DB >> 21507561

Robot-assisted laparoscopic partial adrenalectomy for pheochromocytoma: the National Cancer Institute technique.

Kevin P Asher1, Gopal N Gupta, Ronald S Boris, Peter A Pinto, W Marston Linehan, Gennady Bratslavsky.   

Abstract

BACKGROUND: Partial adrenalectomy has recently been advocated to preserve unaffected adrenal tissue during resection of pheochromocytoma.
OBJECTIVE: To describe a robot-assisted laparoscopic partial adrenalectomy (RALPA) technique and to report on early functional and oncologic outcomes. DESIGN, SETTING, AND PARTICIPANTS: From 2007 to 2010, 15 RALPA were performed on 12 consecutive patients with pheochromocytoma. Follow-up data of >1 yr are available on 11 procedures. Median follow-up for the entire cohort was 17.3 mo (range: 6-45). SURGICAL PROCEDURE: Positioning and port placement is designed for adequate reach and visualization of the upper retroperitoneum. The plane between the adrenal cortex and pheochromocytoma pseudocapsule is identified visually and with laparoscopic ultrasound. The tumor is dissected away from normal adrenal cortex, preserving normal adrenal tissue. MEASUREMENTS: Preoperative, perioperative, pathologic, and functional outcomes data were analyzed. RESULTS AND LIMITATIONS: Fourteen of 15 cases were completed robotically. Among 15 procedures, 4 were performed on a solitary adrenal gland. Four cases required resection of multiple tumors (up to six) with two performed in a solitary gland. The mean age of the patients was 30 yr, and the mean body mass index was 27. The mean operative time was 163 min, the median estimated blood loss was 161 ml, and the median tumor size was 2.7 cm (range: 1.3-5.5). There was one conversion to an open procedure in a patient requiring reoperation on a solitary adrenal gland. One patient who underwent RALPA on a solitary adrenal gland required postoperative steroid supplementation at last follow-up. At a median follow-up of 17.3 mo (range: 6-45), there were no recurrences or metastatic events. Study limitations include small sample size and short follow-up.
CONCLUSIONS: RALPA for the treatment of pheochromocytoma is feasible and safe and provides encouraging functional and oncologic outcomes, even in patients with a solitary adrenal lesion or multiple ipsilateral lesions. Published by Elsevier B.V.

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Mesh:

Year:  2011        PMID: 21507561      PMCID: PMC3109214          DOI: 10.1016/j.eururo.2011.03.046

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


  23 in total

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2.  Laparoscopic adrenalectomy. A new standard of care.

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3.  Laparoscopic adrenalectomy: indications, technique, complications and follow-up.

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4.  Laparoscopic partial adrenalectomy.

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Journal:  Surg Endosc       Date:  1999-04       Impact factor: 4.584

5.  Preserved adrenocortical function after laparoscopic bilateral adrenal sparing surgery for hereditary pheochromocytoma.

Authors:  H P Neumann; M Reincke; B U Bender; R Elsner; G Janetschek
Journal:  J Clin Endocrinol Metab       Date:  1999-08       Impact factor: 5.958

6.  Posterior retroperitoneoscopic partial adrenalectomy: clinical experience in 47 procedures.

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7.  Laparoscopic partial adrenalectomy for recurrent pheochromocytoma after open partial adrenalectomy in von Hippel-Lindau disease.

Authors:  Saif Al-Sobhi; Reinhard Peschel; Christine Zihak; Georg Bartsch; Hartmut Neumann; Günter Janetschek
Journal:  J Endourol       Date:  2002-04       Impact factor: 2.942

8.  Laparoscopic adrenal-sparing surgery for primary hyperaldosteronism due to aldosterone-producing adenoma.

Authors:  K Y Y Kok; S K S Yapp
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9.  Laparoscopic versus open adrenalectomy for surgical adrenal disease.

Authors:  Niels-Erik B Jacobsen; Jeffrey B Campbell; Michael G Hobart
Journal:  Can J Urol       Date:  2003-10       Impact factor: 1.344

10.  Management of hereditary pheochromocytoma in von Hippel-Lindau kindreds with partial adrenalectomy.

Authors:  M M Walther; H R Keiser; P L Choyke; W Rayford; J C Lyne; W M Linehan
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  16 in total

1.  Head docking for single stage robotic cortical sparing adrenalectomy for bilateral pheochromocytoma.

Authors:  Fouad Aoun; Alexandre Peltier; Roland van Velthoven
Journal:  J Robot Surg       Date:  2014-09-04

2.  Perioperative, functional, and oncologic outcomes of partial adrenalectomy for multiple ipsilateral pheochromocytomas.

Authors:  Gopal N Gupta; Jonas S Benson; Michael J Ross; Vani S Sundaram; Kelly Y Lin; Peter A Pinto; W Marston Linehan; Gennady Bratslavsky
Journal:  J Endourol       Date:  2013-10-23       Impact factor: 2.942

3.  SAGES guidelines for minimally invasive treatment of adrenal pathology.

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4.  Partial adrenalectomy minimizes the need for long-term hormone replacement in pediatric patients with pheochromocytoma and von Hippel-Lindau syndrome.

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Journal:  J Pediatr Surg       Date:  2012-11       Impact factor: 2.545

Review 5.  Frontiers in robot-assisted retroperitoneal oncological surgery.

Authors:  Wesley W Ludwig; Michael A Gorin; Phillip M Pierorazio; Mohamad E Allaf
Journal:  Nat Rev Urol       Date:  2017-09-12       Impact factor: 14.432

Review 6.  Robot-assisted adrenalectomy: indications and drawbacks.

Authors:  C Nomine-Criqui; A Germain; A Ayav; L Bresler; L Brunaud
Journal:  Updates Surg       Date:  2017-05-12

Review 7.  The genetic basis of pheochromocytoma and paraganglioma: implications for management.

Authors:  Brian Shuch; Christopher J Ricketts; Adam R Metwalli; Karel Pacak; W Marston Linehan
Journal:  Urology       Date:  2014-03-15       Impact factor: 2.649

8.  Robotic enucleation of adrenal masses: technique and outcomes.

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9.  Long-term Functional and Oncologic Outcomes of Partial Adrenalectomy for Pheochromocytoma.

Authors:  Patrick T Gomella; Thomas H Sanford; Peter A Pinto; Gennady Bratslavsky; Adam R Metwalli; W Marston Linehan; Mark W Ball
Journal:  Urology       Date:  2020-02-26       Impact factor: 2.649

10.  Pheochromocytoma in Urologic Practice.

Authors:  Nikhil Waingankar; Gennady Bratslavsky; Camilo Jimenez; Paul Russo; Alexander Kutikov
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