OBJECTIVE: Managing patients with multiple adrenal masses is technically challenging. We present our experience with minimally invasive partial adrenalectomy (PA) performed for synchronous multiple ipsilateral pheochromocytomas in a single setting. MATERIALS AND METHODS: We reviewed records of patients undergoing PA for pheochromocytoma at the National Cancer Institute between 1994 and 2010. Patients were included if multiple tumors were excised from the ipsilateral adrenal gland in the same operative setting. Perioperative, functional, and oncologic outcomes of PA for multiple pheochromocytomas are shown. RESULTS: Of 121 partial adrenalectomies performed, 10 procedures performed in eight patients for synchronous multiple ipsilateral pheochromocytomas were identified. All eight patients were symptomatic at presentation. The mean patient age was 30.6 years, median follow up was 12 months. The average surgical time was 228 minutes, average blood loss of 125 mL, and average number of tumors removed was 2.6 per adrenal. In total, 26 tumors were removed, 24 were pathologically confirmed pheochromocytomas, while two were adrenal cortical hyperplasia. After surgery, all patients had resolution of their symptoms, one patient required steroid replacement postoperatively. On postoperative imaging, one patient had evidence of ipsilateral adrenal nodule at the prior resection site 2 months postoperatively, which was consistent with incomplete resection. CONCLUSIONS: Minimally invasive surgical resection of synchronous multiple pheochromocytomas is feasible with acceptable perioperative, functional, and short-term oncologic outcomes.
OBJECTIVE: Managing patients with multiple adrenal masses is technically challenging. We present our experience with minimally invasive partial adrenalectomy (PA) performed for synchronous multiple ipsilateral pheochromocytomas in a single setting. MATERIALS AND METHODS: We reviewed records of patients undergoing PA for pheochromocytoma at the National Cancer Institute between 1994 and 2010. Patients were included if multiple tumors were excised from the ipsilateral adrenal gland in the same operative setting. Perioperative, functional, and oncologic outcomes of PA for multiple pheochromocytomas are shown. RESULTS: Of 121 partial adrenalectomies performed, 10 procedures performed in eight patients for synchronous multiple ipsilateral pheochromocytomas were identified. All eight patients were symptomatic at presentation. The mean patient age was 30.6 years, median follow up was 12 months. The average surgical time was 228 minutes, average blood loss of 125 mL, and average number of tumors removed was 2.6 per adrenal. In total, 26 tumors were removed, 24 were pathologically confirmed pheochromocytomas, while two were adrenal cortical hyperplasia. After surgery, all patients had resolution of their symptoms, one patient required steroid replacement postoperatively. On postoperative imaging, one patient had evidence of ipsilateral adrenal nodule at the prior resection site 2 months postoperatively, which was consistent with incomplete resection. CONCLUSIONS: Minimally invasive surgical resection of synchronous multiple pheochromocytomas is feasible with acceptable perioperative, functional, and short-term oncologic outcomes.
Authors: M M Walther; R Reiter; H R Keiser; P L Choyke; D Venzon; K Hurley; J R Gnarra; J C Reynolds; G M Glenn; B Zbar; W M Linehan Journal: J Urol Date: 1999-09 Impact factor: 7.450
Authors: Kevin P Asher; Gopal N Gupta; Ronald S Boris; Peter A Pinto; W Marston Linehan; Gennady Bratslavsky Journal: Eur Urol Date: 2011-04-09 Impact factor: 20.096
Authors: Martin K Walz; Piero F Alesina; Frank A Wenger; J Albrecht Koch; Hartmut P H Neumann; Stephan Petersenn; Kurt W Schmid; Klaus Mann Journal: World J Surg Date: 2006-05 Impact factor: 3.352
Authors: Hartmut P H Neumann; Uliana Tsoy; Irina Bancos; Vincent Amodru; Martin K Walz; Amit Tirosh; Ravinder Jeet Kaur; Travis McKenzie; Xiaoping Qi; Tushar Bandgar; Roman Petrov; Marina Y Yukina; Anna Roslyakova; Anouk N A van der Horst-Schrivers; Annika M A Berends; Ana O Hoff; Luciana Audi Castroneves; Alfonso Massimiliano Ferrara; Silvia Rizzati; Caterina Mian; Sarka Dvorakova; Kornelia Hasse-Lazar; Andrey Kvachenyuk; Mariola Peczkowska; Paola Loli; Feyza Erenler; Tobias Krauss; Madson Q Almeida; Longfei Liu; Feizhou Zhu; Mònica Recasens; Nelson Wohllk; Eleonora P M Corssmit; Zulfiya Shafigullina; Jan Calissendorff; Simona Grozinsky-Glasberg; Tada Kunavisarut; Camilla Schalin-Jäntti; Frederic Castinetti; Petr Vlcek; Dmitry Beltsevich; Viacheslav I Egorov; Francesca Schiavi; Thera P Links; Ronald M Lechan; Birke Bausch; William F Young; Charis Eng Journal: JAMA Netw Open Date: 2019-08-02