Literature DB >> 12559268

Laparoscopic partial adrenalectomy in patients with aldosterone-producing adenomas: indications, technique, and results.

K Jeschke1, G Janetschek, R Peschel, L Schellander, G Bartsch, K Henning.   

Abstract

OBJECTIVES: To report the indications, technique, and results in patients with primary hyperaldosteronism due to aldosterone-producing adrenal adenoma treated by laparoscopic partial adrenalectomy. Laparoscopy has become the technique of choice in adrenal surgery, but adrenalectomy is the standard procedure. Only a few studies have reported on partial adrenalectomy, and the indications and technique have not yet been clearly defined.
METHODS: From June 1995 to December 2001, 13 patients presented with hyperaldosteronism and a single adrenal adenoma (Conn's syndrome) and were treated with laparoscopic partial adrenalectomy. The mean age was 60 years, and the average tumor size was 2.1 cm in diameter. A transperitoneal approach was used in all patients, tumors were resected with safety margins by endoshears, and hemostasis was achieved by bipolar coagulation and finally by sealing with fibrin glue.
RESULTS: All procedures were finished laparoscopically, and no conversion was necessary. No major intraoperative or postoperative complication was observed. The histologic examination showed adenomas with negative surgical margins in all cases. Postoperative computed tomography revealed a normal blood supply for the remaining adrenal tissue. Blood pressure and aldosterone levels were unremarkable at follow-up, and no local recurrence was observed.
CONCLUSIONS: Laparoscopic partial adrenalectomy for aldosterone-producing adenomas is a minimally invasive procedure with a low complication rate. It provides the benefit of retaining functional tissue on the side of the affected adrenal gland. Therefore, we recommend laparoscopic partial adrenalectomy for patients with small, potentially benign, tumors of the adrenal gland, even with a healthy contralateral adrenal gland.

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Year:  2003        PMID: 12559268     DOI: 10.1016/s0090-4295(02)02240-9

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  22 in total

Review 1.  Diagnosis and surgical management for primary hyperaldosteronism.

Authors:  Ravi Munver; Jennifer Yates
Journal:  Curr Urol Rep       Date:  2010-02       Impact factor: 3.092

2.  Retroperitoneoscopic adrenalectomy in Conn's syndrome caused by adrenal adenomas or nodular hyperplasia.

Authors:  Martin K Walz; Roland Gwosdz; Stephanie L Levin; Piero F Alesina; Anna-Carinna Suttorp; Klaus A Metz; Frank A Wenger; Stephan Petersenn; Klaus Mann; Kurt W Schmid
Journal:  World J Surg       Date:  2008-05       Impact factor: 3.352

Review 3.  Robot-assisted laparoscopic partial adrenalectomy: a case report and review of the literature.

Authors:  Jennifer Yates; Jayant Uberoi; Ravi Munver
Journal:  J Robot Surg       Date:  2010-07-22

Review 4.  Adrenal-preserving minimally invasive surgery: update on the current status of laparoscopic partial adrenalectomy.

Authors:  Grant I S Disick; Ravi Munver
Journal:  Curr Urol Rep       Date:  2008-01       Impact factor: 3.092

5.  Partial adrenalectomy minimizes the need for long-term hormone replacement in pediatric patients with pheochromocytoma and von Hippel-Lindau syndrome.

Authors:  Dmitry Volkin; Nitin Yerram; Faisal Ahmed; Dawud Lankford; Angelo Baccala; Gopal N Gupta; Anthony Hoang; Jeffrey Nix; Adam R Metwalli; David M Lang; Gennady Bratslavsky; W Marston Linehan; Peter A Pinto
Journal:  J Pediatr Surg       Date:  2012-11       Impact factor: 2.545

6.  The adrenal psoas sign: surgical outcomes following a simple technique to maximize removal of extracortical adrenal tissue during bilateral laparoscopic adrenalectomy.

Authors:  Erin W Gilbert; Vincent L Harrison; Brett C Sheppard
Journal:  Surg Endosc       Date:  2014-04-25       Impact factor: 4.584

Review 7.  A comprehensive review of the clinical aspects of primary aldosteronism.

Authors:  Gian Paolo Rossi
Journal:  Nat Rev Endocrinol       Date:  2011-05-24       Impact factor: 43.330

8.  Long-term follow-up after adrenalectomy for primary aldosteronism.

Authors:  Andreas Meyer; Georg Brabant; Matthias Behrend
Journal:  World J Surg       Date:  2005-02       Impact factor: 3.352

9.  Robot-assisted laparoscopic partial adrenalectomy: initial experience.

Authors:  Ronald S Boris; Gopal Gupta; W Marston Linehan; Peter A Pinto; Gennady Bratslavsky
Journal:  Urology       Date:  2010-12-03       Impact factor: 2.649

Review 10.  [Adrenalectomy for preservation of adrenocortical function. Indication and results].

Authors:  M K Walz
Journal:  Chirurg       Date:  2009-02       Impact factor: 0.955

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