RuleBender: a visual interface for rule-based modeling.

SUMMARY: Rule-based modeling (RBM) is a powerful and increasingly popular approach to modeling intracellular biochemistry. Current interfaces for RBM are predominantly text-based and command-line driven. Better visual tools are needed to make RBM accessible to a broad range of users, to make specification of models less error prone and to improve workflows. We present RULEBENDER, an open-source visual interface that facilitates interactive debugging, simulation and analysis of RBMs. AVAILABILITY: RULEBENDER is freely available for Mac, Windows and Linux at http://rulebender.org.