Literature DB >> 21486992

Unexpected excessive chronic obstructive pulmonary disease mortality among female silk textile workers in Shanghai, China.

Ling Cui1, Lisa G Gallagher, Roberta M Ray, Wenjin Li, Daoli Gao, Yingzhe Zhang, Sverre Vedal, David B Thomas, Harvey Checkoway.   

Abstract

OBJECTIVE: To investigate chronic obstructive pulmonary disease (COPD) mortality among textile workers.
METHODS: A total of 267,400 Chinese female textile employees were monitored for COPD mortality from 1989 to 2000. Textile factories in the cohort were classified into 10 industrial sectors. Age-adjusted mortality, standardized mortality ratios (SMRs) and 95% CIs were calculated by sector. In addition, RRs (HRs) adjusted for smoking and age were calculated for exposure to cotton and silk textile work compared with the other sectors in the cohort.
RESULTS: A majority of textile sectors had lower or similar COPD mortality (age-adjusted SMRs=0.58-1.15) compared with the general female population in the city of Nanjing, China. SMRs for cotton and silk workers were, respectively, 1.02 (95% CI: 0.81 to 1.28) and 2.03 (95% CI: 1.13 to 3.34). Compared with all other textile sectors in the cohort, there was greater COPD mortality among cotton workers (HR=1.40, 95% CI: 1.03 to 1.89) and silk workers (HR=2.54, 95% CI: 1.47 to 4.39).
CONCLUSION: Elevated COPD mortality among cotton workers is consistent with previous reports of adverse respiratory effects of cotton dust. The higher rate of COPD deaths among silk workers was unexpected.

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Year:  2011        PMID: 21486992      PMCID: PMC3312782          DOI: 10.1136/oem.2010.062034

Source DB:  PubMed          Journal:  Occup Environ Med        ISSN: 1351-0711            Impact factor:   4.402


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