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Literature DB >> 21483661

Syringe-vacuum microfluidics: A portable technique to create monodisperse emulsions.

Abstract

We present a simple method for creating monodisperse emulsions with microfluidic devices. Unlike conventional approaches that require bulky pumps, control computers, and expertise with device physics to operate devices, our method requires only the microfluidic device and a hand-operated syringe. The fluids needed for the emulsion are loaded into the device inlets, while the syringe is used to create a vacuum at the device outlet; this sucks the fluids through the channels, generating the drops. By controlling the hydrodynamic resistances of the channels using hydrodynamic resistors and valves, we are able to control the properties of the drops. This provides a simple and highly portable method for creating monodisperse emulsions.

Year: 2011 PMID： 21483661 PMCID： PMC3073010 DOI： 10.1063/1.3567093

Source DB: PubMed Journal: Biomicrofluidics ISSN： 1932-1058 Impact factor: 2.800

22 in total

10. Creating biocompatible oil-water interfaces without synthesis: direct interactions between primary amines and carboxylated perfluorocarbon surfactants.

Authors: Cheryl J DeJournette; Joonyul Kim; Haley Medlen; Xiangpeng Li; Luke J Vincent; Christopher J Easley
Journal: Anal Chem Date: 2013-10-23 Impact factor: 6.986

Syringe-vacuum microfluidics: A portable technique to create monodisperse emulsions.

1. Microfluidic memory and control devices.

2. Solving the "world-to-chip" interface problem with a microfluidic matrix.

3. High-throughput injection with microfluidics using picoinjectors.

Review 4. Macro-to-micro interfaces for microfluidic devices.

5. Generation of monodisperse particles by using microfluidics: control over size, shape, and composition.

6. Microfluidic flow focusing: drop size and scaling in pressure versus flow-rate-driven pumping.

7. Mixing with bubbles: a practical technology for use with portable microfluidic devices.

8. Impact of inlet channel geometry on microfluidic drop formation.

9. Reliable microfluidic on-chip incubation of droplets in delay-lines.

Review 10. Droplets as microreactors for high-throughput biology.

1. High-performance microfluidic rectifier based on sudden expansion channel with embedded block structure.

2. Simple Bulk Readout of Digital Nucleic Acid Quantification Assays.

3. Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays.

4. A microfluidic gas damper for stabilizing gas pressure in portable microfluidic systems.

5. Micropipette-powered droplet based microfluidics.

Review 6. Advances in microfluidic materials, functions, integration, and applications.

7. Block-and-break generation of microdroplets with fixed volume.

8. Microfluidic rectifier based on poly(dimethylsiloxane) membrane and its application to a micropump.

9. Bubble-free and pulse-free fluid delivery into microfluidic devices.

10. Creating biocompatible oil-water interfaces without synthesis: direct interactions between primary amines and carboxylated perfluorocarbon surfactants.