| Literature DB >> 21459391 |
Sergio Rosselli1, Maurizio Bruno1, Antonella Maggio1, Rosa Angela Raccuglia1, Muhammad Safder2, Chin-Yu Lai3, Kenneth F Bastow4, Kuo-Hsiung Lee5.
Abstract
The analysis of the aerial parts of Bonannia graeca led to the isolation and characterization of polar geranylated flavonoids (6 and 7). The structure elucidation was performed by extensive spectroscopic methods (1D and 2D NMR) and comparison with literature data. All natural flavonoids isolated from B. graeca (1-7) and some synthetic derivatives (8-11) were tested for cytotoxic activity against four human tumor cell lines. Preliminary structure-activity relationship correlations are discussed.Entities:
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Year: 2011 PMID： 21459391 PMCID： PMC3151324 DOI： 10.1016/j.phytochem.2011.03.005
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072