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Literature DB >> 21456968

Controlling mass transport in microfluidic devices.

Abstract

Microfluidic platforms offer exquisite capabilities in controlling mass transport for biological studies. In this review, we focus on recent developments in manipulating chemical concentrations at the microscale. Some techniques prevent or accelerate mixing, whereas others shape the concentration gradients of chemical and biological molecules. We also highlight several in vitro biological studies in the areas of organ engineering, cancer, and blood coagulation that have benefited from accurate control of mass transfer.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21456968 PMCID： PMC5724977 DOI： 10.1146/annurev-anchem-061010-113926

Source DB: PubMed Journal: Annu Rev Anal Chem (Palo Alto Calif) ISSN： 1936-1327 Impact factor: 10.745

108 in total

Controlling mass transport in microfluidic devices.

1. Chemical transformations in individual ultrasmall biomimetic containers.

2. Microfluidic T-form mixer utilizing switching electroosmotic flow.

3. Enhancement of microfluidic mixing using time pulsing.

4. A biohybrid dynamic random access memory.

5. Droplet-based compartmentalization of chemically separated components in two-dimensional separations.

6. A microfluidic device for characterizing the invasion of cancer cells in 3-D matrix.

7. Chemistry and biology in femtoliter and picoliter volume droplets.

8. An agarose-based microfluidic platform with a gradient buffer for 3D chemotaxis studies.

9. Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines.

10. High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry.

1. The potential impact of droplet microfluidics in biology.

Review 2. Microfluidic engineering of exosomes: editing cellular messages for precision therapeutics.

3. Simulating drug concentrations in PDMS microfluidic organ chips.

Review 4. Microfluidics-based on-a-chip systems for isolating and analysing extracellular vesicles.

5. Self-Learning Microfluidic Platform for Single-Cell Imaging and Classification in Flow.

6. Under oil open-channel microfluidics empowered by exclusive liquid repellency.

Review 7. Tissue Chips and Microphysiological Systems for Disease Modeling and Drug Testing.

Review 8. Vessel-on-a-chip models for studying microvascular physiology, transport, and function in vitro.

9. Nanovortex-Driven All-Dielectric Optical Diffusion Boosting and Sorting Concept for Lab-on-a-Chip Platforms.