Literature DB >> 19826654

Droplet-based compartmentalization of chemically separated components in two-dimensional separations.

X Z Niu1, B Zhang, R T Marszalek, O Ces, J B Edel, D R Klug, A J deMello.   

Abstract

We demonstrate that nanolitre-sized droplets are an effective tool in coupling two-dimensional separations in both time and space. Using a microfluidic droplet connector, chemically separated components can be segmented into nanolitre droplets. After oil filtering and droplet merging, these droplets are loaded into a second dimension for comprehensive separations.

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Year:  2009        PMID: 19826654     DOI: 10.1039/b918100h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  19 in total

1.  High-resolution dose-response screening using droplet-based microfluidics.

Authors:  Oliver J Miller; Abdeslam El Harrak; Thomas Mangeat; Jean-Christophe Baret; Lucas Frenz; Bachir El Debs; Estelle Mayot; Michael L Samuels; Eamonn K Rooney; Pierre Dieu; Martin Galvan; Darren R Link; Andrew D Griffiths
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-27       Impact factor: 11.205

2.  A microdroplet dilutor for high-throughput screening.

Authors:  Xize Niu; Fabrice Gielen; Joshua B Edel; Andrew J deMello
Journal:  Nat Chem       Date:  2011-06       Impact factor: 24.427

3.  A simple paper-based sensor fabricated by selective wet etching of silanized filter paper using a paper mask.

Authors:  Longfei Cai; Chunxiu Xu; ShuoHong Lin; Jiating Luo; Meidie Wu; Fan Yang
Journal:  Biomicrofluidics       Date:  2014-10-13       Impact factor: 2.800

4.  Use of a corona discharge to selectively pattern a hydrophilic/hydrophobic interface for integrating segmented flow with microchip electrophoresis and electrochemical detection.

Authors:  Laura A Filla; Douglas C Kirkpatrick; R Scott Martin
Journal:  Anal Chem       Date:  2011-06-30       Impact factor: 6.986

5.  Encapsulation of Fluidic Tubing and Microelectrodes in Microfluidic Devices: Integrating Off-Chip Process and Coupling Conventional Capillary Electrophoresis with Electrochemical Detection.

Authors:  Vedada Becirovic; Steven R Doonan; R Scott Martin
Journal:  Anal Methods       Date:  2013-08-21       Impact factor: 2.896

Review 6.  Controlling mass transport in microfluidic devices.

Authors:  Jason S Kuo; Daniel T Chiu
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2011       Impact factor: 10.745

7.  Fraction collection from capillary liquid chromatography and off-line electrospray ionization mass spectrometry using oil segmented flow.

Authors:  Qiang Li; Jian Pei; Peng Song; Robert T Kennedy
Journal:  Anal Chem       Date:  2010-06-15       Impact factor: 6.986

8.  Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples.

Authors:  Erik D Guetschow; Surinder Kumar; David B Lombard; Robert T Kennedy
Journal:  Anal Bioanal Chem       Date:  2015-12-03       Impact factor: 4.142

9.  Controlled dispensing and mixing of pico- to nanoliter volumes using on-demand droplet-based microfluidics.

Authors:  Xuefei Sun; Keqi Tang; Richard D Smith; Ryan T Kelly
Journal:  Microfluid Nanofluidics       Date:  2013-07-01       Impact factor: 2.529

10.  Capillary liquid chromatography fraction collection and postcolumn reaction using segmented flow microfluidics.

Authors:  Jing Nie; Robert T Kennedy
Journal:  J Sep Sci       Date:  2013-10-09       Impact factor: 3.645

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