Literature DB >> 21453972

Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure.

Misook L Chung1, Terry A Lennie, Rebecca L Dekker, Jia-Rong Wu, Debra K Moser.   

Abstract

BACKGROUND: Depressive symptoms and poor social support are predictors of increased morbidity and mortality in patients with heart failure (HF). However, the combined contribution of depressive symptoms and social support event-free survival of patients with HF has not been examined.
OBJECTIVE: To compare event-free survival in 4 groups of patients with HF stratified by depressive symptoms and perceived social support (PSS).
METHOD: A total of 220 patients completed the Beck Depression Inventory-II and the Multidimensional Perceived Social Support Scale and were followed for up to 4 years to collect data on death and hospitalizations.
RESULTS: Depressive symptoms (hazard ratio = 1.73, P = .008) and PSS (hazard ratio = 1.51, P = .048) were independent predictors of event-free survival. Depressed patients with low PSS had 2.1 times higher risk of events than non-depressed patients with high PSS (P = .003).
CONCLUSION: Depressive symptoms and poor social support had a negative additive effect on event-free survival in patients with HF.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21453972      PMCID: PMC3129423          DOI: 10.1016/j.hrtlng.2010.08.001

Source DB:  PubMed          Journal:  Heart Lung        ISSN: 0147-9563            Impact factor:   2.210


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