PURPOSE: To study the relationship between hip bone mineral density (BMD), lumbar disc degeneration, and lumbar disc space narrowing in elderly subjects. MATERIALS AND METHODS: The study cohort comprised 196 females and 163 males (age range, 67-89 years) with no age difference between the two groups. Anteroposterior total hip areal BMD was measured with DXA and lumbar spine MRI was acquired using a 1.5 Tesla scanner. Lumbar disc degeneration was assessed using an eight-level grading system wherein each grade represents a stepwise progression from normal disc to severe disc degeneration and disc space narrowing. RESULTS: After controlling for the age effect, no significant relationship was observed between total hip T-score status and severity of disc degeneration. There was no significant difference in total hip BMD in the subjects with or without the disc space narrowing (P < 0.05). Female subjects are more likely to have a narrowed disc space than males at all levels, and being statistically significant at L3/4 and L4/5 levels, and with an overall significance of P = 0.007. CONCLUSION: There was no association observed between hip BMD and lumbar disc degeneration. Elderly females were more likely to have a narrowed lumbar disc space than elderly males.
PURPOSE: To study the relationship between hip bone mineral density (BMD), lumbar disc degeneration, and lumbar disc space narrowing in elderly subjects. MATERIALS AND METHODS: The study cohort comprised 196 females and 163 males (age range, 67-89 years) with no age difference between the two groups. Anteroposterior total hip areal BMD was measured with DXA and lumbar spine MRI was acquired using a 1.5 Tesla scanner. Lumbar disc degeneration was assessed using an eight-level grading system wherein each grade represents a stepwise progression from normal disc to severe disc degeneration and disc space narrowing. RESULTS: After controlling for the age effect, no significant relationship was observed between total hip T-score status and severity of disc degeneration. There was no significant difference in total hip BMD in the subjects with or without the disc space narrowing (P < 0.05). Female subjects are more likely to have a narrowed disc space than males at all levels, and being statistically significant at L3/4 and L4/5 levels, and with an overall significance of P = 0.007. CONCLUSION: There was no association observed between hip BMD and lumbar disc degeneration. Elderly females were more likely to have a narrowed lumbar disc space than elderly males.
Authors: Yi-Xiang J Wang; Feng Zhao; James F Griffith; Greta S P Mok; Jason C S Leung; Anil T Ahuja; Jing Yuan Journal: Eur Radiol Date: 2012-08-04 Impact factor: 5.315
Authors: Yi-Xiang J Wang; James F Griffith; Xian-Jun Zeng; Min Deng; Anthony W L Kwok; Jason C S Leung; Anil T Ahuja; Timothy Kwok; Ping Chung Leung Journal: Arthritis Rheum Date: 2013-04
Authors: Astrid Ellen Grams; Rafael Rehwald; Alexander Bartsch; Sarah Honold; Christian Franz Freyschlag; Michael Knoflach; Elke Ruth Gizewski; Bernhard Glodny Journal: BMC Med Imaging Date: 2016-02-24 Impact factor: 1.930