Literature DB >> 21423790

Common statistical concerns in clinical trials.

Scott R Evans1.   

Abstract

Statistics are an integral part of clinical trials. Elements of statistics span clinical trial design, data monitoring, analyses, and reporting. A solid understanding of statistical concepts by clinicians improves the comprehension and the resulting quality of clinical trials. This manuscript outlines common statistical concerns in clinical trials that are important for clinicians to understand.

Entities:  

Year:  2010        PMID： 21423790      PMCID： PMC3059317          DOI： 10.6030/1939-067x-3.1.1

Source DB:  PubMed          Journal:  J Exp Stroke Transl Med        ISSN： 1939-067X


  10 in total

1.  Clinician attitudes toward biostatistics.

Authors:  Colin P West; Robert D Ficalora
Journal:  Mayo Clin Proc       Date:  2007-08       Impact factor: 7.616

2.  Statistical methods in the journal.

Authors:  Nicholas J Horton; Suzanne S Switzer
Journal:  N Engl J Med       Date:  2005-11-03       Impact factor: 91.245

3.  Medicine residents' understanding of the biostatistics and results in the medical literature.

Authors:  Donna M Windish; Stephen J Huot; Michael L Green
Journal:  JAMA       Date:  2007-09-05       Impact factor: 56.272

4.  Absence of evidence is not evidence of absence.

Authors:  D G Altman; J M Bland
Journal:  BMJ       Date:  1995-08-19

5.  Statistical reviewing for medical journals.

Authors:  D G Altman
Journal:  Stat Med       Date:  1998-12-15       Impact factor: 2.373

6.  Confidence intervals rather than P values: estimation rather than hypothesis testing.

Authors:  M J Gardner; D G Altman
Journal:  Br Med J (Clin Res Ed)       Date:  1986-03-15

7.  What do doctors know about statistics?

Authors:  H R Wulff; B Andersen; P Brandenhoff; F Guttler
Journal:  Stat Med       Date:  1987 Jan-Feb       Impact factor: 2.373

8.  When doctors meet numbers.

Authors:  D M Berwick; H V Fineberg; M C Weinstein
Journal:  Am J Med       Date:  1981-12       Impact factor: 4.965

9.  Biostatistics: how to detect, correct and prevent errors in the medical literature.

Authors:  S A Glantz
Journal:  Circulation       Date:  1980-01       Impact factor: 29.690

10.  An assessment of physician knowledge of epidemiology and biostatistics.

Authors:  S T Weiss; J M Samet
Journal:  J Med Educ       Date:  1980-08
  10 in total
  2 in total

1.  CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome.

Authors:  Ashvathi Raghavakaimal; Massimo Cristofanilli; Cha-Mei Tang; R K Alpaugh; Kirby P Gardner; Saranya Chumsri; Daniel L Adams
Journal:  Breast Cancer Res       Date:  2022-05-23       Impact factor: 8.408

2.  Ensuring protocol compliance and data transparency in clinical trials using Blockchain smart contracts.

Authors:  Ilhaam A Omar; Raja Jayaraman; Khaled Salah; Mecit Can Emre Simsekler; Ibrar Yaqoob; Samer Ellahham
Journal:  BMC Med Res Methodol       Date:  2020-09-07       Impact factor: 4.615
  2 in total

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