| Literature DB >> 21414475 |
Adam P Arkin1, David V Schaffer.
Abstract
A decade ago, seminal perspectives and papers set a strong vision for the field of systems biology, and a number of these themes have flourished. Here, we describe key technologies and insights that have elucidated the evolution, architecture, and function of cellular networks, ultimately leading to the first predictive genome-scale regulatory and metabolic models of organisms. Can systems approaches bridge the gap between correlative analysis and mechanistic insights?Mesh：
Year: 2011 PMID： 21414475 DOI： 10.1016/j.cell.2011.03.008
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582