Literature DB >> 21413808

Synopsis of some recent tactical application of bioisosteres in drug design.

Nicholas A Meanwell1.   

Abstract

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Year:  2011        PMID： 21413808     DOI： 10.1021/jm1013693

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  261 in total

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4.  Recent Advances in Transition Metal-Catalyzed Functionalization of gem-Difluoroalkenes.

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Journal:  Isr J Chem       Date:  2020-03-10       Impact factor: 3.333

5.  Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase.

Authors:  Eugene Camerino; Dawn M Wong; Fan Tong; Florian Körber; Aaron D Gross; Rafique Islam; Elisabet Viayna; James M Mutunga; Jianyong Li; Maxim M Totrov; Jeffrey R Bloomquist; Paul R Carlier
Journal:  Bioorg Med Chem Lett       Date:  2015-09-08       Impact factor: 2.823

6.  Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response.

Authors:  Lark J Perez; Wai-Leung Ng; Paul Marano; Karolina Brook; Bonnie L Bassler; Martin F Semmelhack
Journal:  J Med Chem       Date:  2012-11-08       Impact factor: 7.446

7.  Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae.

Authors:  Lark J Perez; Theodora K Karagounis; Amanda Hurley; Bonnie L Bassler; Martin F Semmelhack
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8.  An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.

Authors:  Carol A Mulrooney; David L Lahr; Michael J Quintin; Willmen Youngsaye; Dennis Moccia; Jacob K Asiedu; Evan L Mulligan; Lakshmi B Akella; Lisa A Marcaurelle; Philip Montgomery; Joshua A Bittker; Paul A Clemons; Stephen Brudz; Sivaraman Dandapani; Jeremy R Duvall; Nicola J Tolliday; Andrea De Souza
Journal:  J Comput Aided Mol Des       Date:  2013-04-13       Impact factor: 3.686

9.  Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties.

Authors:  E Jeffrey North; Michael S Scherman; David F Bruhn; Jerrod S Scarborough; Marcus M Maddox; Victoria Jones; Anna Grzegorzewicz; Lei Yang; Tamara Hess; Christophe Morisseau; Mary Jackson; Michael R McNeil; Richard E Lee
Journal:  Bioorg Med Chem       Date:  2013-02-26       Impact factor: 3.641

10.  Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes.

Authors:  Biying Zhou; Moriana K Haj; Eric N Jacobsen; K N Houk; Xiao-Song Xue
Journal:  J Am Chem Soc       Date:  2018-11-05       Impact factor: 15.419
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