Literature DB >> 21411320

A new quinoline derivative with cytotoxic activity from Streptomyces sp. neau50.

Xiang-Jing Wang1, Dian-Liang Gong, Ji-Dong Wang, Ji Zhang, Chong-Xi Liu, Wen-Sheng Xiang.   

Abstract

A new quinoline derivative, methyl 8-(3-methoxy-3-methylbutyl)-2-methylquinoline-4-carboxylate (1), was isolated from the endophytic strain Streptomyces sp. neau50, and the structure was elucidated by extensive spectroscopic analysis. Compound 1 showed cytotoxicity against human lung adenocarcinoma cell line A549 with an IC(50) value of 29.3 μg mL(-1).
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21411320     DOI: 10.1016/j.bmcl.2011.02.095

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

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Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-08-01
  4 in total

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