Literature DB >> 2141093

Metabolic dynamics in the human red cell. Part III--Metabolic reaction rates.

A Joshi1, B O Palsson.   

Abstract

The kinetics of the enzymatic reaction and transport rates that constitute the main metabolic pathways of the red cell metabolism are described. The red cell metabolic model consists of 33 dynamic mass balances that contain 41 enzymatic reaction rate laws and transmembrane processes. Our goal here is two-fold: the development of rate expressions for the individual biochemical reactions of the integrated red cell metabolism, and order of magnitudes estimates to gauge their dynamic properties in terms of response times and action scales of substrates, products and regulators.

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Year:  1990        PMID: 2141093     DOI: 10.1016/s0022-5193(05)80012-8

Source DB:  PubMed          Journal:  J Theor Biol        ISSN: 0022-5193            Impact factor:   2.691


  20 in total

1.  Description and analysis of metabolic connectivity and dynamics in the human red blood cell.

Authors:  Kenneth J Kauffman; John David Pajerowski; Neema Jamshidi; Bernhard O Palsson; Jeremy S Edwards
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033

2.  Extreme pathway analysis of human red blood cell metabolism.

Authors:  Sharon J Wiback; Bernhard O Palsson
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033

Review 3.  The computational integrated myocyte: a view into the virtual heart.

Authors:  James B Bassingthwaighte; Kalyan C Vinnakota
Journal:  Ann N Y Acad Sci       Date:  2004-05       Impact factor: 5.691

4.  The modelling of a primitive 'sustainable' conservative cell.

Authors:  James B Bassingthwaighte
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2001-06       Impact factor: 4.226

5.  Mass action stoichiometric simulation models: incorporating kinetics and regulation into stoichiometric models.

Authors:  Neema Jamshidi; Bernhard Ø Palsson
Journal:  Biophys J       Date:  2010-01-20       Impact factor: 4.033

6.  Changes in glucose uptake rather than lactate shuttle take center stage in subserving neuroenergetics: evidence from mathematical modeling.

Authors:  Mauro DiNuzzo; Silvia Mangia; Bruno Maraviglia; Federico Giove
Journal:  J Cereb Blood Flow Metab       Date:  2009-11-04       Impact factor: 6.200

7.  Bioengineering, the integrating discipline.

Authors:  J B Bassingthwaighte
Journal:  Ann Biomed Eng       Date:  1994 May-Jun       Impact factor: 3.934

8.  Network-level analysis of metabolic regulation in the human red blood cell using random sampling and singular value decomposition.

Authors:  Christian L Barrett; Nathan D Price; Bernhard O Palsson
Journal:  BMC Bioinformatics       Date:  2006-03-13       Impact factor: 3.169

9.  Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

Authors:  Germán Plata; Tzu-Lin Hsiao; Kellen L Olszewski; Manuel Llinás; Dennis Vitkup
Journal:  Mol Syst Biol       Date:  2010-09-07       Impact factor: 11.429

10.  Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110.

Authors:  A Varma; B O Palsson
Journal:  Appl Environ Microbiol       Date:  1994-10       Impact factor: 4.792

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