Literature DB >> 21385435

compomics-utilities: an open-source Java library for computational proteomics.

Harald Barsnes1, Marc Vaudel, Niklaas Colaert, Kenny Helsens, Albert Sickmann, Frode S Berven, Lennart Martens.   

Abstract

BACKGROUND: The growing interest in the field of proteomics has increased the demand for software tools and applications that process and analyze the resulting data. And even though the purpose of these tools can vary significantly, they usually share a basic set of features, including the handling of protein and peptide sequences, the visualization of (and interaction with) spectra and chromatograms, and the parsing of results from various proteomics search engines. Developers typically spend considerable time and effort implementing these support structures, which detracts from working on the novel aspects of their tool.
RESULTS: In order to simplify the development of proteomics tools, we have implemented an open-source support library for computational proteomics, called compomics-utilities. The library contains a broad set of features required for reading, parsing, and analyzing proteomics data. compomics-utilities is already used by a long list of existing software, ensuring library stability and continued support and development.
CONCLUSIONS: As a user-friendly, well-documented and open-source library, compomics-utilities greatly simplifies the implementation of the basic features needed in most proteomics tools. Implemented in 100% Java, compomics-utilities is fully portable across platforms and architectures. Our library thus allows the developers to focus on the novel aspects of their tools, rather than on the basic functions, which can contribute substantially to faster development, and better tools for proteomics.

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Year:  2011        PMID: 21385435      PMCID: PMC3060842          DOI: 10.1186/1471-2105-12-70

Source DB:  PubMed          Journal:  BMC Bioinformatics        ISSN: 1471-2105            Impact factor:   3.169


  19 in total

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4.  DBToolkit: processing protein databases for peptide-centric proteomics.

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Journal:  Bioinformatics       Date:  2005-07-19       Impact factor: 6.937

5.  ProteomeCommons.org IO Framework: reading and writing multiple proteomics data formats.

Authors:  J A Falkner; J W Falkner; P C Andrews
Journal:  Bioinformatics       Date:  2006-11-22       Impact factor: 6.937

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8.  ProteoWizard: open source software for rapid proteomics tools development.

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9.  mzML--a community standard for mass spectrometry data.

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5.  Relative Abundance of Proteins in Blood Plasma Samples from Patients with Chronic Cerebral Ischemia.

Authors:  Anna L Kaysheva; Artur T Kopylov; Elena A Ponomarenko; Olga I Kiseleva; Nadezhda B Teryaeva; Alexander A Potapov; Alexander А Izotov; Sergei G Morozov; Valeria Yu Kudryavtseva; Alexander I Archakov
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7.  DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics.

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8.  APOSTL: An Interactive Galaxy Pipeline for Reproducible Analysis of Affinity Proteomics Data.

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9.  Unveiling novel interactions of histone chaperone Asf1 linked to TREX-2 factors Sus1 and Thp1.

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