Literature DB >> 21362566

Phosphoryl-EZH-ion.

Giuseppina Caretti1, Daniela Palacios, Vittorio Sartorelli, Pier Lorenzo Puri.   

Abstract

Polycomb group (PcG) proteins regulate gene expression in embryonic and adult stem cells, but the mechanisms responsible for PcG gene targeting and regulation remain largely unknown. Recent evidence shows that EZH2, the enzymatic subunit of Polycomb Repressive Complex 2 (PRC2), is a nuclear phosphoprotein linking cell-cycle-intrinsic or extracellular signals to specific epigenetic signatures.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21362566      PMCID： PMC3166223          DOI： 10.1016/j.stem.2011.02.012

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  24 in total

1.  A tissue-specific atlas of mouse protein phosphorylation and expression.

Authors:  Edward L Huttlin; Mark P Jedrychowski; Joshua E Elias; Tapasree Goswami; Ramin Rad; Sean A Beausoleil; Judit Villén; Wilhelm Haas; Mathew E Sowa; Steven P Gygi
Journal:  Cell       Date:  2010-12-23       Impact factor: 41.582

2.  A quantitative atlas of mitotic phosphorylation.

Authors:  Noah Dephoure; Chunshui Zhou; Judit Villén; Sean A Beausoleil; Corey E Bakalarski; Stephen J Elledge; Steven P Gygi
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-31       Impact factor: 11.205

3.  Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

Authors:  Viveka Mayya; Deborah H Lundgren; Sun-Il Hwang; Karim Rezaul; Linfeng Wu; Jimmy K Eng; Vladimir Rodionov; David K Han
Journal:  Sci Signal       Date:  2009-08-18       Impact factor: 8.192

4.  Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA.

Authors:  Syuzo Kaneko; Gang Li; Jinsook Son; Chong-Feng Xu; Raphael Margueron; Thomas A Neubert; Danny Reinberg
Journal:  Genes Dev       Date:  2010-12-01       Impact factor: 11.361

5.  Phosphoproteomic analysis of human embryonic stem cells.

Authors:  Laurence M Brill; Wen Xiong; Ki-Bum Lee; Scott B Ficarro; Andrew Crain; Yue Xu; Alexey Terskikh; Evan Y Snyder; Sheng Ding
Journal:  Cell Stem Cell       Date:  2009-08-07       Impact factor: 24.633

6.  CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells.

Authors:  Yongkun Wei; Ya-Huey Chen; Long-Yuan Li; Jingyu Lang; Su-Peng Yeh; Bin Shi; Cheng-Chieh Yang; Jer-Yen Yang; Chun-Yi Lin; Chien-Chen Lai; Mien-Chie Hung
Journal:  Nat Cell Biol       Date:  2010-12-05       Impact factor: 28.824

7.  Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2.

Authors:  Shuai Chen; Laura R Bohrer; Aswathy N Rai; Yunqian Pan; Lu Gan; Xianzheng Zhou; Anindya Bagchi; Jeffrey A Simon; Haojie Huang
Journal:  Nat Cell Biol       Date:  2010-10-10       Impact factor: 28.824

Review 8.  Chromatin: the interface between extrinsic cues and the epigenetic regulation of muscle regeneration.

Authors:  Valentina Guasconi; Pier Lorenzo Puri
Journal:  Trends Cell Biol       Date:  2009-04-23       Impact factor: 20.808

9.  Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.

Authors:  Elena Ezhkova; H Amalia Pasolli; Joel S Parker; Nicole Stokes; I-hsin Su; Gregory Hannon; Alexander Tarakhovsky; Elaine Fuchs
Journal:  Cell       Date:  2009-03-20       Impact factor: 41.582

10.  Talking to chromatin: post-translational modulation of polycomb group function.

Authors:  Hanneke E C Niessen; Jeroen A Demmers; Jan Willem Voncken
Journal:  Epigenetics Chromatin       Date:  2009-09-01       Impact factor: 4.954
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  12 in total

1.  EZH2: a pivotal regulator in controlling cell differentiation.

Authors:  Ya-Huey Chen; Mien-Chie Hung; Long-Yuan Li
Journal:  Am J Transl Res       Date:  2012-10-10       Impact factor: 4.060

Review 2.  Role of EZH2 histone methyltrasferase in melanoma progression and metastasis.

Authors:  Fade Mahmoud; Bradley Shields; Issam Makhoul; Laura F Hutchins; Sara C Shalin; Alan J Tackett
Journal:  Cancer Biol Ther       Date:  2016-04-22       Impact factor: 4.742

3.  The roles of EZH2 in cell lineage commitment.

Authors:  Ruey-Hwang Chou; Yung-Luen Yu; Mien-Chie Hung
Journal:  Am J Transl Res       Date:  2011-04-21       Impact factor: 4.060

4.  AMPK lifts the PRC2-implemented gene repression.

Authors:  Tao Han; Qing Yin; Lixin Wan
Journal:  Mol Cell Oncol       Date:  2018-04-04

Review 5.  PRC2 during vertebrate organogenesis: a complex in transition.

Authors:  Issam Aldiri; Monica L Vetter
Journal:  Dev Biol       Date:  2012-05-04       Impact factor: 3.582

6.  Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation.

Authors:  Silvia Consalvi; Arianna Brancaccio; Alessandra Dall'Agnese; Pier Lorenzo Puri; Daniela Palacios
Journal:  Nat Commun       Date:  2017-01-09       Impact factor: 14.919

7.  Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer.

Authors:  Cristina Segovia; Mónica Martínez-Fernández; Marta Dueñas; Carolina Rubio; Fernando F López-Calderón; Clotilde Costa; Cristina Saiz-Ladera; María Fernández-Grajera; José Duarte; Huberto García Muñoz; Federico de la Rosa; Felipe Villacampa; Daniel Castellano; Jesús M Paramio
Journal:  Oncotarget       Date:  2017-02-07

8.  The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state.

Authors:  J Manuel Hernández-Hernández; Chandrashekara Mallappa; Brian T Nasipak; Steffi Oesterreich; Anthony N Imbalzano
Journal:  Nucleic Acids Res       Date:  2013-04-22       Impact factor: 16.971

9.  The histone H3K27 methylation mark regulates intestinal epithelial cell density-dependent proliferation and the inflammatory response.

Authors:  Naomie Turgeon; Mylène Blais; Jean-François Delabre; Claude Asselin
Journal:  J Cell Biochem       Date:  2013-05       Impact factor: 4.429

Review 10.  Epigenomics of cancer - emerging new concepts.

Authors:  Melanie R Hassler; Gerda Egger
Journal:  Biochimie       Date:  2012-05-17       Impact factor: 4.079
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