PURPOSE: The aim of the present study was to evaluate the performance of multidetector-row CT (MDCT) and magnetic resonance imaging (MRI) in diagnosing hepatocellular carcinoma (HCC) preoperatively in living related liver transplantation (LRLT) recipients with liver cirrhosis and HCC. MATERIALS AND METHODS: A total of 25 LRLT recipients with 89 pathologically proved HCCs underwent dynamic 4-row MDCT (5 mm collimation) and MRI within 1 month before LRLT. The images were reviewed for the diagnosis of HCC on a tumor-by-tumor basis by three observers independently and randomly using explanted specimens as the gold standard. The diagnostic accuracy of these techniques in the detection of HCC was assessed with alternative free response receiver operating characteristic (ROC) analysis. The sensitivity and positive predictive values were evaluated. RESULTS: The average values of the area under the ROC curve (Az) of MRI images were higher than those obtained with MDCT; however, no significant difference was observed (P > 0.05). The overall sensitivity of HCC with MRI was higher than that with MDCT, especially in the case of HCCs <20 mm. CONCLUSION: A better diagnostic performance regarding HCCs in LRLT recipients was achieved with MRI than with MDCT, although no significant difference was observed.
PURPOSE: The aim of the present study was to evaluate the performance of multidetector-row CT (MDCT) and magnetic resonance imaging (MRI) in diagnosing hepatocellular carcinoma (HCC) preoperatively in living related liver transplantation (LRLT) recipients with liver cirrhosis and HCC. MATERIALS AND METHODS: A total of 25 LRLT recipients with 89 pathologically proved HCCs underwent dynamic 4-row MDCT (5 mm collimation) and MRI within 1 month before LRLT. The images were reviewed for the diagnosis of HCC on a tumor-by-tumor basis by three observers independently and randomly using explanted specimens as the gold standard. The diagnostic accuracy of these techniques in the detection of HCC was assessed with alternative free response receiver operating characteristic (ROC) analysis. The sensitivity and positive predictive values were evaluated. RESULTS: The average values of the area under the ROC curve (Az) of MRI images were higher than those obtained with MDCT; however, no significant difference was observed (P > 0.05). The overall sensitivity of HCC with MRI was higher than that with MDCT, especially in the case of HCCs <20 mm. CONCLUSION: A better diagnostic performance regarding HCCs in LRLT recipients was achieved with MRI than with MDCT, although no significant difference was observed.
Authors: F Y Yao; L Ferrell; N M Bass; J J Watson; P Bacchetti; A Venook; N L Ascher; J P Roberts Journal: Hepatology Date: 2001-06 Impact factor: 17.425
Authors: Seong Hyun Kim; Dongil Choi; Seung Hoon Kim; Jae Hoon Lim; Won Jae Lee; Min Ju Kim; Hyo K Lim; Soon Jin Lee Journal: AJR Am J Roentgenol Date: 2005-04 Impact factor: 3.959
Authors: D Maluf; R A Fisher; T Maroney; A Cotterell; A Fulcher; J Tisnado; M Contos; V Luketic; R Stravitz; M Shiffman; R Sterling; M Posner Journal: Am J Transplant Date: 2003-03 Impact factor: 8.086
Authors: Vo Tan Duc; Phan Cong Chien; Le Duy Mai Huyen; Tran Le Minh Chau; Nguyen Do Trung Chanh; Duong Thi Minh Soan; Hoang Cao Huyen; Huynh Minh Thanh; Le Nguyen Gia Hy; Nguyen Hoang Nam; Mai Thi Tu Uyen; Le Huu Hanh Nhi; Le Huu Nhat Minh Journal: Cureus Date: 2022-01-17