| Literature DB >> 21343463 |
Michelle M Nerandzic1, Curtis J Donskey.
Abstract
Ceftobiprole and ceftobiprole medocaril did not promote growth of or toxin production by Clostridium difficile in mouse cecal contents, whereas ceftazidime, cefoxitin, ceftriaxone, cefotaxime, and ertapenem did. The relatively low propensity of ceftobiprole to promote C. difficile was attributable to inhibitory activity against C. difficile and sparing of anaerobic microflora.Entities:
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Year: 2011 PMID: 21343463 PMCID: PMC3088227 DOI: 10.1128/AAC.01612-10
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191