Literature DB >> 17043115

Effect of carbapenem administration on establishment of intestinal colonization by vancomycin-resistant enterococci and Klebsiella pneumoniae in mice.

Usha Stiefel1, Nicole J Pultz, Curtis J Donskey.   

Abstract

In a mouse model, ertapenem inhibited the anaerobic intestinal microflora and promoted overgrowth of enterococci, whereas imipenem-cilastatin had no effect on the indigenous microflora. Ertapenem, but not imipenem-cilastatin, promoted modest overgrowth of vancomycin-resistant enterococci when exposure occurred during treatment. Neither agent promoted colonization with extended-spectrum beta-lactamase-producing Klebsiella pneumoniae.

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Year:  2006        PMID： 17043115      PMCID： PMC1797675          DOI： 10.1128/AAC.00355-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

Review 1.  The role of the intestinal tract as a reservoir and source for transmission of nosocomial pathogens.

Authors:  Curtis J Donskey
Journal:  Clin Infect Dis       Date:  2004-06-25       Impact factor: 9.079

2.  Effect of meropenem on the intestinal microflora.

Authors:  T Bergan; C E Nord; S B Thorsteinsson
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-06       Impact factor: 3.267

3.  Bowel colonization with resistant gram-negative bacilli after antimicrobial therapy of intra-abdominal infections: observations from two randomized comparative clinical trials of ertapenem therapy.

Authors:  M J Dinubile; I Friedland; C Y Chan; M R Motyl; H Giezek; M Shivaprakash; R A Weinstein; J P Quinn
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2005-07       Impact factor: 3.267

4.  Effect of parenteral antibiotic administration on persistence of vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract.

Authors:  C J Donskey; J A Hanrahan; R A Hutton; L B Rice
Journal:  J Infect Dis       Date:  1999-08       Impact factor: 5.226

Review 5.  Effect of antimicrobial agents on the ecological balance of human microflora.

Authors:  A Sullivan; C Edlund; C E Nord
Journal:  Lancet Infect Dis       Date:  2001-09       Impact factor: 25.071

6.  Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers.

Authors:  Mathias W R Pletz; Mareike Rau; Juergen Bulitta; Andres De Roux; Olaf Burkhardt; Guido Kruse; Michael Kurowski; Carl E Nord; Hartmut Lode
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

7.  Effect of parenteral antibiotic administration on establishment of intestinal colonization in mice by Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases.

Authors:  Claudia K Hoyen; Nicole J Pultz; David L Paterson; David C Aron; Curtis J Donskey
Journal:  Antimicrob Agents Chemother       Date:  2003-11       Impact factor: 5.191

8.  Effect of imipenem/cilastatin on the colonic microflora.

Authors:  C E Nord; L Kager; A Philipson; G Stiernstedt
Journal:  Rev Infect Dis       Date:  1985 Jul-Aug

9.  Impact of imipenem/cilastatin therapy on normal fecal flora.

Authors:  H M Wexler; S M Finegold
Journal:  Am J Med       Date:  1985-06-07       Impact factor: 4.965
  9 in total
  7 in total

1.  Effects of imipenem-cilastatin, ertapenem, piperacillin-tazobactam, and ceftriaxone treatments on persistence of intestinal colonization by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae strains in mice.

Authors:  Michael J Pultz; Curtis J Donskey
Journal:  Antimicrob Agents Chemother       Date:  2007-06-11       Impact factor: 5.191

2.  Effect of ceftobiprole treatment on growth of and toxin production by Clostridium difficile in cecal contents of mice.

Authors:  Michelle M Nerandzic; Curtis J Donskey
Journal:  Antimicrob Agents Chemother       Date:  2011-02-22       Impact factor: 5.191

3.  Gastrointestinal colonization with a cephalosporinase-producing bacteroides species preserves colonization resistance against vancomycin-resistant enterococcus and Clostridium difficile in cephalosporin-treated mice.

Authors:  Usha Stiefel; Michelle M Nerandzic; Michael J Pultz; Curtis J Donskey
Journal:  Antimicrob Agents Chemother       Date:  2014-05-27       Impact factor: 5.191

4.  A murine model to study the gut bacteria parameters during complex antibiotics like cefotaxime and ceftriaxone treatment.

Authors:  Matthieu Grégoire; Florian Berteau; Ronan Bellouard; Quentin Lebastard; Philippe Aubert; Jacques Gonzales; François Javaudin; Anne Bessard; Pascale Bemer; Éric Batard; Didier Lepelletier; Michel Neunlist; Emmanuel Montassier; Éric Dailly
Journal:  Comput Struct Biotechnol J       Date:  2021-03-04       Impact factor: 7.271

Review 5.  Piperacillin-tazobactam as alternative to carbapenems for ICU patients.

Authors:  Benoit Pilmis; Vincent Jullien; Alexis Tabah; Jean-Ralph Zahar; Christian Brun-Buisson
Journal:  Ann Intensive Care       Date:  2017-11-10       Impact factor: 6.925

6.  Continuous increase of vancomycin resistance in enterococci causing nosocomial infections in Germany - 10 years of surveillance.

Authors:  Cornelius Remschmidt; Christin Schröder; Michael Behnke; Petra Gastmeier; Christine Geffers; Tobias Siegfried Kramer
Journal:  Antimicrob Resist Infect Control       Date:  2018-04-24       Impact factor: 4.887

7.  Antimicrobial Stewardship Program: Reducing Antibiotic's Spectrum of Activity Is not the Solution to Limit the Emergence of Multidrug-Resistant Bacteria.

Authors:  Rindala Saliba; Assaf Mizrahi; Péan de Ponfilly Gauthier; Le Monnier Alban; Jean-Ralph Zahar; Benoît Pilmis
Journal:  Antibiotics (Basel)       Date:  2022-01-07
  7 in total

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