Literature DB >> 21333845

Genomics for disease treatment and prevention.

Cinnamon S Bloss1, Dilip V Jeste, Nicholas J Schork.   

Abstract

The enormous advances in genetics and genomics of the past decade have the potential to revolutionize health care, including mental health care, and bring about a system predominantly characterized by the practice of genomic and personalized medicine. This article briefly reviews the history of genetics and genomics and assesses the extent to which the results of genetic and genomic studies are currently being leveraged clinically for disease treatment and prevention. Relevant social, economic, and policy issues relevant to genomic medicine are also reviewed, and priority research areas in which further work is needed are identified.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21333845      PMCID: PMC3073546          DOI: 10.1016/j.psc.2010.11.005

Source DB:  PubMed          Journal:  Psychiatr Clin North Am        ISSN: 0193-953X


  72 in total

1.  Personal genomics services: whose genomes?

Authors:  David Gurwitz; Yael Bregman-Eschet
Journal:  Eur J Hum Genet       Date:  2009-03-04       Impact factor: 4.246

Review 2.  The HapMap and genome-wide association studies in diagnosis and therapy.

Authors:  Teri A Manolio; Francis S Collins
Journal:  Annu Rev Med       Date:  2009       Impact factor: 13.739

Review 3.  The role of genetic variation in the causation of mental illness: an evolution-informed framework.

Authors:  R Uher
Journal:  Mol Psychiatry       Date:  2009-08-25       Impact factor: 15.992

4.  An agenda for personalized medicine.

Authors:  Pauline C Ng; Sarah S Murray; Samuel Levy; J Craig Venter
Journal:  Nature       Date:  2009-10-08       Impact factor: 49.962

5.  Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose.

Authors:  Mark J Rieder; Alexander P Reiner; Brian F Gage; Deborah A Nickerson; Charles S Eby; Howard L McLeod; David K Blough; Kenneth E Thummel; David L Veenstra; Allan E Rettie
Journal:  N Engl J Med       Date:  2005-06-02       Impact factor: 91.245

6.  Estimation of effect size distribution from genome-wide association studies and implications for future discoveries.

Authors:  Ju-Hyun Park; Sholom Wacholder; Mitchell H Gail; Ulrike Peters; Kevin B Jacobs; Stephen J Chanock; Nilanjan Chatterjee
Journal:  Nat Genet       Date:  2010-06-20       Impact factor: 38.330

7.  Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.

Authors:  Neil Risch; Richard Herrell; Thomas Lehner; Kung-Yee Liang; Lindon Eaves; Josephine Hoh; Andrea Griem; Maria Kovacs; Jurg Ott; Kathleen Ries Merikangas
Journal:  JAMA       Date:  2009-06-17       Impact factor: 56.272

Review 8.  Finding the missing heritability of complex diseases.

Authors:  Teri A Manolio; Francis S Collins; Nancy J Cox; David B Goldstein; Lucia A Hindorff; David J Hunter; Mark I McCarthy; Erin M Ramos; Lon R Cardon; Aravinda Chakravarti; Judy H Cho; Alan E Guttmacher; Augustine Kong; Leonid Kruglyak; Elaine Mardis; Charles N Rotimi; Montgomery Slatkin; David Valle; Alice S Whittemore; Michael Boehnke; Andrew G Clark; Evan E Eichler; Greg Gibson; Jonathan L Haines; Trudy F C Mackay; Steven A McCarroll; Peter M Visscher
Journal:  Nature       Date:  2009-10-08       Impact factor: 49.962

9.  Genetic variation in healthy oldest-old.

Authors:  Julius Halaschek-Wiener; Mahsa Amirabbasi-Beik; Nasim Monfared; Markus Pieczyk; Christian Sailer; Anita Kollar; Ruth Thomas; Georgios Agalaridis; So Yamada; Lisa Oliveira; Jennifer A Collins; Graydon Meneilly; Marco A Marra; Kenneth M Madden; Nhu D Le; Joseph M Connors; Angela R Brooks-Wilson
Journal:  PLoS One       Date:  2009-08-14       Impact factor: 3.240

10.  Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.

Authors:  Shaun M Purcell; Naomi R Wray; Jennifer L Stone; Peter M Visscher; Michael C O'Donovan; Patrick F Sullivan; Pamela Sklar
Journal:  Nature       Date:  2009-07-01       Impact factor: 49.962

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  10 in total

Review 1.  Direct-to-consumer personalized genomic testing.

Authors:  Cinnamon S Bloss; Burcu F Darst; Eric J Topol; Nicholas J Schork
Journal:  Hum Mol Genet       Date:  2011-08-09       Impact factor: 6.150

Review 2.  The importance of gene-environment interactions in human obesity.

Authors:  Hudson Reddon; Jean-Louis Guéant; David Meyre
Journal:  Clin Sci (Lond)       Date:  2016-09-01       Impact factor: 6.124

3.  Public knowledge of and attitudes toward genetics and genetic testing.

Authors:  Susanne B Haga; William T Barry; Rachel Mills; Geoffrey S Ginsburg; Laura Svetkey; Jennifer Sullivan; Huntington F Willard
Journal:  Genet Test Mol Biomarkers       Date:  2013-02-13

Review 4.  Four Actionable Bottlenecks and Potential Solutions to Translating Psychiatric Genetics Research: An Expert Review.

Authors:  Jessica L Bourdon; Rachel A Davies; Elizabeth C Long
Journal:  Public Health Genomics       Date:  2020-11-04       Impact factor: 2.000

5.  In-vivo design feedback and perceived utility of a genetically-informed smoking risk tool among current smokers in the community.

Authors:  Jessica L Bourdon; Amelia Dorsey; Maia Zalik; Amanda Pietka; Patricia Salyer; Michael J Bray; Laura J Bierut; Alex T Ramsey
Journal:  BMC Med Genomics       Date:  2021-05-26       Impact factor: 3.063

6.  Development of a communication protocol for telephone disclosure of genetic test results for cancer predisposition.

Authors:  Linda J Patrick-Miller; Brian L Egleston; Dominique Fetzer; Andrea Forman; Lisa Bealin; Christina Rybak; Candace Peterson; Melanie Corbman; Julio Albarracin; Evelyn Stevens; Mary B Daly; Angela R Bradbury
Journal:  JMIR Res Protoc       Date:  2014-10-29

Review 7.  Assessing the Costs and Cost-Effectiveness of Genomic Sequencing.

Authors:  Kurt D Christensen; Dmitry Dukhovny; Uwe Siebert; Robert C Green
Journal:  J Pers Med       Date:  2015-12-10

Review 8.  Genomics of Particulate Matter Exposure Associated Cardiopulmonary Disease: A Narrative Review.

Authors:  Julia Citron; Emma Willcocks; George Crowley; Sophia Kwon; Anna Nolan
Journal:  Int J Environ Res Public Health       Date:  2019-11-07       Impact factor: 3.390

Review 9.  Genomics Education in the Era of Personal Genomics: Academic, Professional, and Public Considerations.

Authors:  Kiara V Whitley; Josie A Tueller; K Scott Weber
Journal:  Int J Mol Sci       Date:  2020-01-24       Impact factor: 5.923

10.  The Nigerian Bioinformatics and Genomics Network (NBGN): a collaborative platform to advance bioinformatics and genomics in Nigeria.

Authors:  Segun Fatumo; ThankGod E Ebenezer; Chinwe Ekenna; Itunuoluwa Isewon; Umar Ahmad; Charles Adetunji; Elijah Kolawole Oladipo; Marion Adebiyi; Ezekiel Adebiyi; Oyekanmi Nashiru
Journal:  Glob Health Epidemiol Genom       Date:  2020-07-15
  10 in total

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