| Literature DB >> 21332131 |
Juan Zou1, Lutai Pan, Qiji Li, Junhua Zhao, Jianxin Pu, Ping Yao, Ningbo Gong, Yang Lu, Tamara P Kondratyuk, John M Pezzuto, Harry H S Fong, Hongjie Zhang, Handong Sun.
Abstract
From the medicinal plant Isodon rubescens, we isolated two novel diterpenes, rubesanolides A (1) and B (2). The compounds contain a unique β-lactone subgroup. This is the first discovery for a natural diterpene having rings A, B, and C in chair, boat, and twist-chair conformations, respectively. The structures were elucidated by analysis of spectroscopic data, and the absolute configuration of 1 was determined by X-ray diffraction.Entities:
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Year: 2011 PMID： 21332131 PMCID： PMC3057937 DOI： 10.1021/ol200086k
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005