Literature DB >> 21318902

Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.

Jatinder S Josan1, Channa R De Silva, Byunghee Yoo, Ronald M Lynch, Mark D Pagel, Josef Vagner, Victor J Hruby.   

Abstract

The use of fluorescent (or luminescent) and metal contrast agents in high-throughput screens, in vitro assays, and molecular imaging procedures has rapidly expanded in recent years. Here we describe the development and utility of high-affinity ligands for cancer theranostics and other in vitro screening -studies. In this context, we also illustrate the syntheses and use of heteromultivalent ligands as targeted imaging agents.

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Year:  2011        PMID: 21318902      PMCID: PMC3365840          DOI: 10.1007/978-1-61779-012-6_6

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  38 in total

1.  Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors.

Authors:  Paolo Grieco; Antonio Lavecchia; Minying Cai; Devendra Trivedi; David Weinberg; Tanya MacNeil; L H T Van der Ploeg; Victor J Hruby
Journal:  J Med Chem       Date:  2002-11-21       Impact factor: 7.446

Review 2.  Detection strategies for bioassays based on luminescent lanthanide complexes and signal amplification.

Authors:  Tanja Steinkamp; Uwe Karst
Journal:  Anal Bioanal Chem       Date:  2004-08-05       Impact factor: 4.142

Review 3.  Optical spectroscopy for detection of neoplasia.

Authors:  Konstantin Sokolov; Michele Follen; Rebecca Richards-Kortum
Journal:  Curr Opin Chem Biol       Date:  2002-10       Impact factor: 8.822

4.  The monitoring of reactions in solid-phase peptide synthesis with picric acid.

Authors:  B F Gisin
Journal:  Anal Chim Acta       Date:  1972-01       Impact factor: 6.558

Review 5.  Lanthanide-based luminescent assays for ligand-receptor interactions.

Authors:  Heather L Handl; Robert J Gillies
Journal:  Life Sci       Date:  2005-02-19       Impact factor: 5.037

6.  An amine-derivatized, DOTA-loaded polymeric support for Fmoc Solid Phase Peptide Synthesis.

Authors:  Byunghee Yoo; Vipul R Sheth; Mark D Pagel
Journal:  Tetrahedron Lett       Date:  2009-08-05       Impact factor: 2.415

7.  Using two chemical exchange saturation transfer magnetic resonance imaging contrast agents for molecular imaging studies.

Authors:  M Meser Ali; Guanshu Liu; Tejas Shah; Chris A Flask; Mark D Pagel
Journal:  Acc Chem Res       Date:  2009-07-21       Impact factor: 22.384

Review 8.  The synthesis and chelation chemistry of DOTA-peptide conjugates.

Authors:  Luis M De León-Rodríguez; Zoltan Kovacs
Journal:  Bioconjug Chem       Date:  2007-12-12       Impact factor: 4.774

Review 9.  Excitement in f block: structure, dynamics and function of nine-coordinate chiral lanthanide complexes in aqueous media.

Authors:  David Parker
Journal:  Chem Soc Rev       Date:  2004-02-13       Impact factor: 54.564

10.  PARACEST MRI with improved temporal resolution.

Authors:  Guanshu Liu; M Meser Ali; Byunghee Yoo; Mark A Griswold; Jean A Tkach; Mark D Pagel
Journal:  Magn Reson Med       Date:  2009-02       Impact factor: 4.668

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  10 in total

1.  Delta-Opioid Receptor (δOR) Targeted Near-Infrared Fluorescent Agent for Imaging of Lung Cancer: Synthesis and Evaluation In Vitro and In Vivo.

Authors:  Allison S Cohen; Renata Patek; Steven A Enkemann; Joseph O Johnson; Tingan Chen; Eric Toloza; Josef Vagner; David L Morse
Journal:  Bioconjug Chem       Date:  2015-10-30       Impact factor: 4.774

2.  Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis.

Authors:  Justin Hoffman; Andrea N Flynn; Dipti V Tillu; Zhenyu Zhang; Renata Patek; Theodore J Price; Josef Vagner; Scott Boitano
Journal:  Bioconjug Chem       Date:  2012-10-08       Impact factor: 4.774

3.  Melanocortin 1 Receptor-Targeted α-Particle Therapy for Metastatic Uveal Melanoma.

Authors:  Narges K Tafreshi; Christopher J Tichacek; Darpan N Pandya; Michael L Doligalski; Mikalai M Budzevich; HyunJoo Kil; Nikunj B Bhatt; Nancy D Kock; Jane L Messina; Epifanio E Ruiz; Nella C Delva; Adam Weaver; William R Gibbons; David C Boulware; Nikhil I Khushalani; Ghassan El-Haddad; Pierre L Triozzi; Eduardo G Moros; Mark L McLaughlin; Thaddeus J Wadas; David L Morse
Journal:  J Nucl Med       Date:  2019-02-07       Impact factor: 10.057

4.  Hetero-bivalent GLP-1/glibenclamide for targeting pancreatic β-cells.

Authors:  Nathaniel J Hart; Woo Jin Chung; Craig Weber; Kameswari Ananthakrishnan; Miranda Anderson; Renata Patek; Zhanyu Zhang; Sean W Limesand; Josef Vagner; Ronald M Lynch
Journal:  Chembiochem       Date:  2013-11-20       Impact factor: 3.164

5.  Synthesis and bioactivity of MSH4 oligomers prepared by an A2 + B2 strategy.

Authors:  Dilani Chathurika Dehigaspitiya; Suryakiran Navath; Craig S Weber; Ronald M Lynch; Eugene A Mash
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

6.  A nano-sized PARACEST-fluorescence imaging contrast agent facilitates and validates in vivo CEST MRI detection of glioma.

Authors:  Meser M Ali; Mohammed Pi Bhuiyan; Branislava Janic; Nadimpalli Rs Varma; Tom Mikkelsen; James R Ewing; Robert A Knight; Mark D Pagel; Ali S Arbab
Journal:  Nanomedicine (Lond)       Date:  2012-08-14       Impact factor: 5.307

7.  Detecting in vivo urokinase plasminogen activator activity with a catalyCEST MRI contrast agent.

Authors:  Sanhita Sinharay; Christine M Howison; Amanda F Baker; Mark D Pagel
Journal:  NMR Biomed       Date:  2017-03-29       Impact factor: 4.044

8.  A Synthetic Heterobivalent Ligand Composed of Glucagon-Like Peptide 1 and Yohimbine Specifically Targets β Cells Within the Pancreas.

Authors:  Leah V Steyn; Kameswari Ananthakrishnan; Miranda J Anderson; Renata Patek; Amy Kelly; Josef Vagner; Ronald M Lynch; Sean W Limesand
Journal:  Mol Imaging Biol       Date:  2015-01-21       Impact factor: 3.488

9.  Sensing lanthanide metal content in biological tissues with magnetic resonance spectroscopy.

Authors:  Dina V Hingorani; Sandra I Gonzalez; Jessica F Li; Mark D Pagel
Journal:  Sensors (Basel)       Date:  2013-10-11       Impact factor: 3.576

10.  Heteropentanuclear Oxalato-Bridged nd-4f (n=4, 5) Metal Complexes with NO Ligand: Synthesis, Crystal Structures, Aqueous Stability and Antiproliferative Activity.

Authors:  Paul-Steffen Kuhn; Laura Cremer; Anatolie Gavriluta; Katarina K Jovanović; Lana Filipović; Alfred A Hummer; Gabriel E Büchel; Biljana P Dojčinović; Samuel M Meier; Annette Rompel; Siniša Radulović; Jean Bernard Tommasino; Dominique Luneau; Vladimir B Arion
Journal:  Chemistry       Date:  2015-08-10       Impact factor: 5.236

  10 in total

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