Literature DB >> 21318443

Sigmoid diverticulitis in young patients--a more aggressive disease than in older patients?

Jörg-Peter Ritz1, Kai S Lehmann, Andrea Stroux, Heinz J Buhr, Christoph Holmer.   

Abstract

INTRODUCTION: There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis. PATIENTS AND METHODS: Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010.
RESULTS: A total of 1,019 patients were included: 513 (69 ≤40 years and 444 >40 years) presented with their first episode, while 506 (20 ≤40 years, 486 >40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%, p = 0.875; free perforation, 26.1% vs. 23.9%, p = 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%, p = 0.287; free perforation, 5% vs. 4.1%, p = 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%, p = 0.690) or the recurrent episode (5% vs. 4.1%, p = 0.846). No differences in the rate of Hartmann's procedure (52.6% vs. 68.3%, p = 0.180) and failure of conservative treatment (3.4% vs. 4.9%, p = 0.607) were observed between younger and older patients.
CONCLUSION: Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.

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Year:  2011        PMID: 21318443     DOI: 10.1007/s11605-011-1457-2

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  33 in total

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  12 in total

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Authors:  Christoph Holmer; Kai S Lehmann; Sabrina Engelmann; Jörn Gröne; Heinz J Buhr; Jörg-Peter Ritz
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