J-P Ritz1, J Gröne, S Engelmann, K S Lehmann, H J Buhr, C Holmer. 1. Klinik für Allgemein-, Gefäß- und Thoraxchirurgie, Chirurgische Klinik I, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland.
Abstract
INTRODUCTION: The correct therapeutic management of acute sigmoid diverticulitis (SD) is still controversially discussed. Essential to the success of therapy is primarily the long-term resolution of Patient symptoms after surgical or conservative therapy. The aim of this study was to compare the long-term outcome after conservative and surgical treatment of Patients with acute SD. PATIENTS AND METHODS: Consecutive admissions of all Patients with acute SD were prospectively recruited from January 2005 to June 2008 with the exception of a free perforation. The following data were recorded: age, sex, first or recurrent episode of SD, computed tomography (CT) stage, white blood cell count, C-reactive protein, persistent symptoms and recurrence after conservative and surgical therapy. Furthermore, information on the rates of postoperative sexual and bladder dysfunction was collected. The long-term outcome was evaluated by a standardized questionnaire. In June 2008 all Patients were contacted using a standardized questionnaire. RESULTS: A total of 153 Patients were included in the study of whom 70 (45.8 %) presented with the first episode, 83 (54.2 %) had a prior history of SD and 40 Patients were treated conservatively whereas 113 Patients were surgically treated by sigmoid resection. Uncomplicated SD was seen in 16 Patients (conservative 4, surgical 12, p = 0.961), phlegmonous SD was seen in 88 cases (conservative 29, surgical 59, p = 0.026) and covered perforated SD in 49 cases (conservative 7, surgical 42, p = 0.022). The median follow-up was 32 months (range 12-52 months). At follow-up 25 % of conservative and 8.8 % of Patients treated surgically complained about persistent symptoms (p = 0.009). The following symptoms occurred (conservative vs. surgery): painful defecation (22.5 % versus 8.8 %, p = 0.024.), constipation (25 % versus 8.8 %, p = 0.009), abdominal cramp (22.5 % versus 4.4 %, p = 0.001) and painful flatulence (25 % versus 8.8 %, p = 0.009). Sexual or bladder dysfunction occurred postoperatively in 7 % and 9 %, respectively. Of the conservatively treated Patients 32.5 % had a recurrence of SD during follow-up compared to 3.5 % of surgically treated Patients (p < 0.001). CONCLUSIONS: Surgical treatment of acute SD is more effective than conservative therapy for the prophylaxis of recurrent SD and avoidance of persistent symptoms.
INTRODUCTION: The correct therapeutic management of acute sigmoid diverticulitis (SD) is still controversially discussed. Essential to the success of therapy is primarily the long-term resolution of Patient symptoms after surgical or conservative therapy. The aim of this study was to compare the long-term outcome after conservative and surgical treatment of Patients with acute SD. PATIENTS AND METHODS: Consecutive admissions of all Patients with acute SD were prospectively recruited from January 2005 to June 2008 with the exception of a free perforation. The following data were recorded: age, sex, first or recurrent episode of SD, computed tomography (CT) stage, white blood cell count, C-reactive protein, persistent symptoms and recurrence after conservative and surgical therapy. Furthermore, information on the rates of postoperative sexual and bladder dysfunction was collected. The long-term outcome was evaluated by a standardized questionnaire. In June 2008 all Patients were contacted using a standardized questionnaire. RESULTS: A total of 153 Patients were included in the study of whom 70 (45.8 %) presented with the first episode, 83 (54.2 %) had a prior history of SD and 40 Patients were treated conservatively whereas 113 Patients were surgically treated by sigmoid resection. Uncomplicated SD was seen in 16 Patients (conservative 4, surgical 12, p = 0.961), phlegmonous SD was seen in 88 cases (conservative 29, surgical 59, p = 0.026) and covered perforated SD in 49 cases (conservative 7, surgical 42, p = 0.022). The median follow-up was 32 months (range 12-52 months). At follow-up 25 % of conservative and 8.8 % of Patients treated surgically complained about persistent symptoms (p = 0.009). The following symptoms occurred (conservative vs. surgery): painful defecation (22.5 % versus 8.8 %, p = 0.024.), constipation (25 % versus 8.8 %, p = 0.009), abdominal cramp (22.5 % versus 4.4 %, p = 0.001) and painful flatulence (25 % versus 8.8 %, p = 0.009). Sexual or bladder dysfunction occurred postoperatively in 7 % and 9 %, respectively. Of the conservatively treated Patients 32.5 % had a recurrence of SD during follow-up compared to 3.5 % of surgically treated Patients (p < 0.001). CONCLUSIONS: Surgical treatment of acute SD is more effective than conservative therapy for the prophylaxis of recurrent SD and avoidance of persistent symptoms.
Authors: Mary Panjari; Robin J Bell; Susan Burney; Stephen Bell; Paul J McMurrick; Susan R Davis Journal: J Sex Med Date: 2012-08-20 Impact factor: 3.802
Authors: Johannes C Lauscher; Johan F Lock; Katja Aschenbrenner; Rahel M Strobel; Marja Leonhardt; Andrea Stroux; Benjamin Weixler; Christoph-Thomas Germer; Martin E Kreis Journal: Int J Colorectal Dis Date: 2020-09-04 Impact factor: 2.571