Literature DB >> 21311016

On the future of genomic data.

Scott D Kahn1.   

Abstract

Many of the challenges in genomics derive from the informatics needed to store and analyze the raw sequencing data that is available from highly multiplexed sequencing technologies. Because single week-long sequencing runs today can produce as much data as did entire genome centers a few years ago, the need to process terabytes of information has become de rigueur for many labs engaged in genomic research. The availability of deep (and large) genomic data sets raises concerns over information access, data security, and subject/patient privacy that must be addressed for the field to continue its rapid advances.

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Year:  2011        PMID: 21311016     DOI: 10.1126/science.1197891

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  66 in total

1.  Compressive genomics.

Authors:  Po-Ru Loh; Michael Baym; Bonnie Berger
Journal:  Nat Biotechnol       Date:  2012-07-10       Impact factor: 54.908

Review 2.  Bacterial genome sequencing in the clinic: bioinformatic challenges and solutions.

Authors:  W Florian Fricke; David A Rasko
Journal:  Nat Rev Genet       Date:  2013-11-26       Impact factor: 53.242

Review 3.  Privacy challenges and research opportunities for genomic data sharing.

Authors:  Luca Bonomi; Yingxiang Huang; Lucila Ohno-Machado
Journal:  Nat Genet       Date:  2020-06-29       Impact factor: 38.330

4.  Swarm: A federated cloud framework for large-scale variant analysis.

Authors:  Amir Bahmani; Kyle Ferriter; Vandhana Krishnan; Arash Alavi; Amir Alavi; Philip S Tsao; Michael P Snyder; Cuiping Pan
Journal:  PLoS Comput Biol       Date:  2021-05-12       Impact factor: 4.475

5.  Advances in computer simulation of genome evolution: toward more realistic evolutionary genomics analysis by approximate bayesian computation.

Authors:  Miguel Arenas
Journal:  J Mol Evol       Date:  2015-03-26       Impact factor: 2.395

6.  Quality score compression improves genotyping accuracy.

Authors:  Y William Yu; Deniz Yorukoglu; Jian Peng; Bonnie Berger
Journal:  Nat Biotechnol       Date:  2015-03       Impact factor: 54.908

7.  Meeting the challenge: Health information technology's essential role in achieving precision medicine.

Authors:  Teresa Zayas-Cabán; Kevin J Chaney; Courtney C Rogers; Joshua C Denny; P Jon White
Journal:  J Am Med Inform Assoc       Date:  2021-06-12       Impact factor: 4.497

8.  Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow.

Authors:  Elizabeth Brunk; Roger L Chang; Jing Xia; Hooman Hefzi; James T Yurkovich; Donghyuk Kim; Evan Buckmiller; Harris H Wang; Byung-Kwan Cho; Chen Yang; Bernhard O Palsson; George M Church; Nathan E Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-09       Impact factor: 11.205

Review 9.  The changing epitome of species identification - DNA barcoding.

Authors:  M Ajmal Ali; Gábor Gyulai; Norbert Hidvégi; Balázs Kerti; Fahad M A Al Hemaid; Arun K Pandey; Joongku Lee
Journal:  Saudi J Biol Sci       Date:  2014-03-31       Impact factor: 4.219

10.  Merging of multi-string BWTs with applications.

Authors:  James Holt; Leonard McMillan
Journal:  Bioinformatics       Date:  2014-08-28       Impact factor: 6.937

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