PURPOSE OF REVIEW: As spectral-domain optical coherence tomography (SD-OCT) progressively replaces time-domain OCT (TD-OCT) in the clinical and research setting, several commercially available instruments and new software upgrades for glaucoma diagnosis and progression analysis have been developed. Over the last year, several studies have been performed to assess the diagnostic performance of most of these instruments necessitating a review of their findings. RECENT FINDINGS: When compared with the measurements provided by TD-OCT, the conventional peripapillary circular scans by SD-OCT, which aim to measure the retinal nerve fiber layer (RNFL) thickness, show higher repeatability and similar diagnostic sensitivity. New software capabilities, such as the RNFL deviation map of Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) or the macular Ganglion Cell Complex scan of RTVue (Optovue, Fremont, CA), provide complementary information that enhances our ability to discriminate between healthy and glaucomatous eyes. SUMMARY: SD-OCT-based instruments represent a technological advancement in the diagnosis of glaucoma. Improved repeatability will facilitate more reliable follow-up and progression analysis.
PURPOSE OF REVIEW: As spectral-domain optical coherence tomography (SD-OCT) progressively replaces time-domain OCT (TD-OCT) in the clinical and research setting, several commercially available instruments and new software upgrades for glaucoma diagnosis and progression analysis have been developed. Over the last year, several studies have been performed to assess the diagnostic performance of most of these instruments necessitating a review of their findings. RECENT FINDINGS: When compared with the measurements provided by TD-OCT, the conventional peripapillary circular scans by SD-OCT, which aim to measure the retinal nerve fiber layer (RNFL) thickness, show higher repeatability and similar diagnostic sensitivity. New software capabilities, such as the RNFL deviation map of Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) or the macular Ganglion Cell Complex scan of RTVue (Optovue, Fremont, CA), provide complementary information that enhances our ability to discriminate between healthy and glaucomatous eyes. SUMMARY: SD-OCT-based instruments represent a technological advancement in the diagnosis of glaucoma. Improved repeatability will facilitate more reliable follow-up and progression analysis.
Authors: Adam L Rothman; Monica B Sevilla; Sharon F Freedman; Amy Y Tong; Vincent Tai; Du Tran-Viet; Sina Farsiu; Cynthia A Toth; Mays A El-Dairi Journal: Am J Ophthalmol Date: 2015-01-26 Impact factor: 5.258
Authors: Ali S Raza; Xian Zhang; Carlos G V De Moraes; Charles A Reisman; Jeffrey M Liebmann; Robert Ritch; Donald C Hood Journal: Invest Ophthalmol Vis Sci Date: 2014-01-29 Impact factor: 4.799
Authors: Mingwu Wang; Ake Tzu-Hui Lu; Rohit Varma; Joel S Schuman; David S Greenfield; David Huang Journal: J Glaucoma Date: 2014-03 Impact factor: 2.503
Authors: Akram Belghith; Christopher Bowd; Felipe A Medeiros; Madhusudhanan Balasubramanian; Robert N Weinreb; Linda M Zangwill Journal: J Med Imaging (Bellingham) Date: 2014-12-29