Literature DB >> 21302903

N-acylsulfonamide assisted tandem C-H olefination/annulation: synthesis of isoindolinones.

Chen Zhu1, J R Falck.   

Abstract

A tandem C-H olefination/annulation sequence directed by N-acylsulfonamides affords a variety of isoindolinones. This transformation is compatible with aliphatic alkenes as well as conjugated alkenes. Notably, molecular oxygen can be used as the sole, eco-friendly oxidant.

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Year:  2011        PMID： 21302903      PMCID： PMC3045675          DOI： 10.1021/ol200093f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


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  12 in total

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Review 8.  Developing ligands for palladium(II)-catalyzed C-H functionalization: intimate dialogue between ligand and substrate.

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