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Literature DB >> 21278188

PiNGO: a Cytoscape plugin to find candidate genes in biological networks.

Michael Smoot¹, Keiichiro Ono, Trey Ideker, Steven Maere.

Abstract

UNLABELLED: PiNGO is a tool to screen biological networks for candidate genes, i.e. genes predicted to be involved in a biological process of interest. The user can narrow the search to genes with particular known functions or exclude genes belonging to particular functional classes. PiNGO provides support for a wide range of organisms and Gene Ontology classification schemes, and it can easily be customized for other organisms and functional classifications. PiNGO is implemented as a plugin for Cytoscape, a popular network visualization platform. AVAILABILITY: PiNGO is distributed as an open-source Java package under the GNU General Public License (http://www.gnu.org/), and can be downloaded via the Cytoscape plugin manager. A detailed user guide and tutorial are available on the PiNGO website (http://www.psb.ugent.be/esb/PiNGO.

Mesh：

Year: 2011 PMID： 21278188 PMCID： PMC3065683 DOI： 10.1093/bioinformatics/btr045

Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937

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5. Tracing the footsteps of autophagy in computational biology.

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8. Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice.

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10. Pivotal role of the muscle-contraction pathway in cryptorchidism and evidence for genomic connections with cardiomyopathy pathways in RASopathies.

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