BACKGROUND & AIMS: The size of polyps found on computed tomography colonography (CTC) has been suggested as the major determinant of patient management. We compared polyp size as seen on CTC with endoscopic visualization, in vivo probe measurement, and ex vivo size before and after fixation. METHODS: Polyps measured on CTC sent for endoscopic removal were evaluated for polyp size in a blinded fashion by endoscopic estimation, in vivo probe measurement, and after removal. RESULTS: Fifty-six polyps were included in the study. There was no significant difference between CTC polyp size, real-time colonoscopy size estimation, or probe measurement. The size of polyp measured immediately ex vivo and after pathology fixation was significantly smaller. Management would be altered in 6 of 56 polyps (10.7%) on the basis of differences between size of the polyp on endoscopy and CTC. CONCLUSIONS: (1) CTC polyp size measurement is not significantly different from colonoscopy in vivo visual estimation and linear probe measurement. (2) Differences in size of polyps as measured on CTC and endoscopy will affect patient management in 10% of cases.
BACKGROUND & AIMS: The size of polyps found on computed tomography colonography (CTC) has been suggested as the major determinant of patient management. We compared polyp size as seen on CTC with endoscopic visualization, in vivo probe measurement, and ex vivo size before and after fixation. METHODS:Polyps measured on CTC sent for endoscopic removal were evaluated for polyp size in a blinded fashion by endoscopic estimation, in vivo probe measurement, and after removal. RESULTS: Fifty-six polyps were included in the study. There was no significant difference between CTC polyp size, real-time colonoscopy size estimation, or probe measurement. The size of polyp measured immediately ex vivo and after pathology fixation was significantly smaller. Management would be altered in 6 of 56 polyps (10.7%) on the basis of differences between size of the polyp on endoscopy and CTC. CONCLUSIONS: (1) CTC polyp size measurement is not significantly different from colonoscopy in vivo visual estimation and linear probe measurement. (2) Differences in size of polyps as measured on CTC and endoscopy will affect patient management in 10% of cases.
Authors: Charlotte J Tutein Nolthenius; Thierry N Boellaard; Margriet C de Haan; C Yung Nio; Maarten G J Thomeer; Shandra Bipat; Alexander D Montauban van Swijndregt; Marc J van de Vijver; Katharina Biermann; Ernst J Kuipers; Evelien Dekker; Jaap Stoker Journal: Am J Gastroenterol Date: 2015-10-20 Impact factor: 10.864
Authors: Perry J Pickhardt; David H Kim; B Dustin Pooler; J Louis Hinshaw; Duncan Barlow; Don Jensen; Mark Reichelderfer; Brooks D Cash Journal: Lancet Oncol Date: 2013-06-07 Impact factor: 41.316
Authors: Samir Gupta; Bijal A Balasubramanian; Tommy Fu; Robert M Genta; Don C Rockey; Richard Lash Journal: Clin Gastroenterol Hepatol Date: 2012-07-24 Impact factor: 11.382