Literature DB >> 21274246

Management of breast cancer: what do I tell the patient?

C J Wright.   

Abstract

Controversies exist about management of breast cancer because different conclusions are drawn from the same sets of data. Evidence now shows that conservative methods of treatment give the same results as aggressive surgery, especially when combined with radiation, so the question is not which operation is best, but how this knowledge can be disseminated. The surgeon and patient should be fully aware of the options for reconstruction. The next big question concerns prophylactic radiotherapy, which awaits a convincing randomized controlled trial of its effectiveness. Long-term benefits of adjuvant chemotherapy are unknown, but costs (both physical and financial) are well known. Patients must be given access to data on risk factors for developing breast cancer, especially so-called 'precancerous' lesions. Screening of all women is still a debatable topic, although all women with risk factors should be screened. They should be frankly told that prognosis can only be based on statistical probability.

Entities:  

Year:  1986        PMID: 21274246      PMCID: PMC2327585     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  17 in total

1.  Conservative Treatment of Cancer of the Breast.

Authors:  G Keynes
Journal:  Br Med J       Date:  1937-10-02

2.  Lobular carcinoma in situ of the breast. Detailed analysis of 99 patients with average follow-up of 24 years.

Authors:  P P Rosen; C Kosloff; P H Lieberman; F Adair; D W Braun
Journal:  Am J Surg Pathol       Date:  1978-09       Impact factor: 6.394

Review 3.  Lobular neoplasia (so-called lobular carcinoma in situ) of the breast.

Authors:  C D Haagensen; N Lane; R Lattes; C Bodian
Journal:  Cancer       Date:  1978-08       Impact factor: 6.860

4.  Conservative treatment of breast carcinoma--review of 25 years follow up.

Authors:  S Mustakallio
Journal:  Clin Radiol       Date:  1972-01       Impact factor: 2.350

5.  Adjuvant chemotherapy in breast cancer.

Authors:  G Bonadonna; A Rossi; G Tancini; P Valagussa
Journal:  Lancet       Date:  1983-05-21       Impact factor: 79.321

6.  Is aggressive adjuvant chemotherapy the Halsted radical of the '80s?

Authors:  R Kushner
Journal:  CA Cancer J Clin       Date:  1984 Nov-Dec       Impact factor: 508.702

Review 7.  Treatment of primary breast cancer without mastectomy. Review of the literature.

Authors:  A Z Bluming
Journal:  Am J Med       Date:  1982-05       Impact factor: 4.965

8.  L-phenylalanine mustard (L-PAM) in the management of primary breast cancer. An update of earlier findings and a comparison with those utilizing L-PAM plus 5-fluorouracil (5-FU).

Authors:  B Fisher; A Glass; C Redmond; E R Fisher; B Barton; E Such; P Carbone; S Economou; R Foster; R Frelick; H Lerner; M Levitt; R Margolese; J MacFarlane; D Plotkin; H Shibata; H Volk
Journal:  Cancer       Date:  1977-06       Impact factor: 6.860

9.  Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast.

Authors:  U Veronesi; R Saccozzi; M Del Vecchio; A Banfi; C Clemente; M De Lena; G Gallus; M Greco; A Luini; E Marubini; G Muscolino; F Rilke; B Salvadori; A Zecchini; R Zucali
Journal:  N Engl J Med       Date:  1981-07-02       Impact factor: 91.245

10.  Reduction in mortality from breast cancer after mass screening with mammography. Randomised trial from the Breast Cancer Screening Working Group of the Swedish National Board of Health and Welfare.

Authors:  L Tabár; C J Fagerberg; A Gad; L Baldetorp; L H Holmberg; O Gröntoft; U Ljungquist; B Lundström; J C Månson; G Eklund
Journal:  Lancet       Date:  1985-04-13       Impact factor: 79.321

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