Literature DB >> 21270372

Challenges and new opportunities for clinical nutrition interventions in the aged.

Mary Ann Johnson1, Johanna T Dwyer, Gordon L Jensen, Joshua W Miller, John R Speakman, Pamela Starke-Reed, Elena Volpi.   

Abstract

Nutritional status plays a critical role in the prevention and management of many chronic health conditions that are common in the elderly and are likely to become more prevalent as the population ages. This paper highlights several aspects of nutrition that require additional basic science and clinical application research to improve the health and well-being of older adults. Topics addressed are selected demographic and health indices, the uncertain benefits of energy restriction in aged humans compared with other species, the impact of food insecurity on health, the relationship between dietary protein and sarcopenia, the prevention and management of obesity while maintaining muscle mass and functional status, and controversy regarding high intakes of folic acid. Research needs regarding the safety, efficacy, and application of clinical interventions related to these topics also are discussed.

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Year:  2011        PMID： 21270372      PMCID： PMC3138222          DOI： 10.3945/jn.110.131425

Source DB:  PubMed          Journal:  J Nutr        ISSN： 0022-3166            Impact factor:   4.798


  78 in total

1.  Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification.

Authors:  Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Journal:  Am J Clin Nutr       Date:  2007-01       Impact factor: 7.045

2.  Cognitive impairment in older Americans in the age of folic acid fortification.

Authors:  Robert J Berry; Heather K Carter; Quanhe Yang
Journal:  Am J Clin Nutr       Date:  2007-07       Impact factor: 7.045

Review 3.  Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan.

Authors:  John R Speakman; Catherine Hambly
Journal:  J Nutr       Date:  2007-04       Impact factor: 4.798

4.  A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly.

Authors:  Christos S Katsanos; Hisamine Kobayashi; Melinda Sheffield-Moore; Asle Aarsland; Robert R Wolfe
Journal:  Am J Physiol Endocrinol Metab       Date:  2006-02-28       Impact factor: 4.310

5.  Caloric restriction increases longevity substantially only when the reaction norm is steep.

Authors:  John P Phelan; Michael R Rose
Journal:  Biogerontology       Date:  2006-06       Impact factor: 4.277

6.  Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling.

Authors:  Satoshi Fujita; Blake B Rasmussen; Jerson G Cadenas; Micah J Drummond; Erin L Glynn; Fred R Sattler; Elena Volpi
Journal:  Diabetes       Date:  2007-03-09       Impact factor: 9.461

7.  Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis.

Authors:  Senada Arabelovic; Gina Sam; Gerard E Dallal; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg; Ronenn Roubenoff
Journal:  J Am Coll Nutr       Date:  2007-10       Impact factor: 3.169

8.  A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis.

Authors:  Joel B Mason; Aaron Dickstein; Paul F Jacques; Paul Haggarty; Jacob Selhub; Gerard Dallal; Irwin H Rosenberg
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2007-07       Impact factor: 4.254

9.  Reduction in neural-tube defects after folic acid fortification in Canada.

Authors:  Philippe De Wals; Fassiatou Tairou; Margot I Van Allen; Soo-Hong Uh; R Brian Lowry; Barbara Sibbald; Jane A Evans; Michiel C Van den Hof; Pamela Zimmer; Marian Crowley; Bridget Fernandez; Nora S Lee; Theophile Niyonsenga
Journal:  N Engl J Med       Date:  2007-07-12       Impact factor: 91.245

10.  Caloric restriction does not enhance longevity in all species and is unlikely to do so in humans.

Authors:  Daryl P Shanley; Thomas B L Kirkwood
Journal:  Biogerontology       Date:  2006-06       Impact factor: 4.277
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  3 in total

1.  The aromatic amino acid tryptophan stimulates skeletal muscle IGF1/p70s6k/mTor signaling in vivo and the expression of myogenic genes in vitro.

Authors:  Amy Dukes; Colleen Davis; Mona El Refaey; Sunil Upadhyay; Sarah Mork; Phonepasong Arounleut; Maribeth H Johnson; William D Hill; Carlos M Isales; Mark W Hamrick
Journal:  Nutrition       Date:  2015-03-17       Impact factor: 4.008

Review 2.  Glutamine metabolism in advanced age.

Authors:  Dominique Meynial-Denis
Journal:  Nutr Rev       Date:  2016-03-02       Impact factor: 7.110

Review 3.  Healthy Aging-Nutrition Matters: Start Early and Screen Often.

Authors:  Susan B Roberts; Rachel E Silver; Sai Krupa Das; Roger A Fielding; Cheryl H Gilhooly; Paul F Jacques; Jennifer M Kelly; Joel B Mason; Nicola M McKeown; Meaghan A Reardon; Sheldon Rowan; Edward Saltzman; Barbara Shukitt-Hale; Caren E Smith; Allen A Taylor; Dayong Wu; Fang Fang Zhang; Karen Panetta; Sarah Booth
Journal:  Adv Nutr       Date:  2021-07-30       Impact factor: 8.701
  3 in total

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