| Literature DB >> 21269620 |
Beth W Rackow1, Elisa Jorgensen, Hugh S Taylor.
Abstract
This case-control study evaluated the effect of hysteroscopically identified endometrial polyps on endometrium by means of HOXA10 and HOXA11, known molecular markers of endometrial receptivity. Uteri with endometrial polyps demonstrated a marked decrease in HOXA10 and HOXA11 messenger RNA levels, which may impair implantation. These findings suggest a molecular mechanism to support the clinical findings of diminished pregnancy rates in women with endometrial polyps.Entities:
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Year: 2011 PMID: 21269620 PMCID: PMC3096716 DOI: 10.1016/j.fertnstert.2010.12.034
Source DB: PubMed Journal: Fertil Steril ISSN: 0015-0282 Impact factor: 7.329