Literature DB >> 21269392

What is the definition of a satisfactory erectile function after bilateral nerve sparing radical prostatectomy?

Alberto Briganti1, Andrea Gallina, Nazareno Suardi, Umberto Capitanio, Manuela Tutolo, Marco Bianchi, Andrea Salonia, Renzo Colombo, Valerio Di Girolamo, Juan Ignazio Martinez-Salamanca, Giorgio Guazzoni, Patrizio Rigatti, Francesco Montorsi.   

Abstract

INTRODUCTION: Different cut-offs of the erectile function (EF) domain of the International Index of Erectile Function (IIEF) have been used as definition of postoperative EF recovery. AIM: To test the correlation between patient satisfaction and IIEF-EF domain score cut-offs. MAIN OUTCOME MEASURE: The IIEF was used to evaluate EF and satisfaction before and after bilateral nerve sparing radical prostatectomy (BNSRP).
METHODS: The study included 165 consecutive patients treated with retropubic BNSRP at a single institution. All patients had normal preoperative EF (IIEF-EF ≥ 26) and reached an IIEF-EF ≥ 17 following surgery. Complete data included EF, intercourse (IS), and overall satisfaction (OS) assessed by the corresponding domains of the IIEF administered prior and after surgery. Patients were divided into three groups according to the highest IIEF-EF score reached postoperatively, namely 17-21 (group 1), 22-25 (group 2), and ≥ 26 (group 3). One-way analysis of variance was used to compare IIEF-OS and IIEF-IS domain scores at the time the EF end point was reached. The same analyses were repeated separately in those patients with a complete EF recovery after surgery (group 3).
RESULTS: Mean preoperative IIEF-OS and IIEF-IS domain score was 8.4, 8.8, 8.7 and 11.6, 11.8, 11.9 in group 1, 2, 3, respectively (all P ≥ 0.3). After a mean follow-up of 26.7 months, mean postoperative IIEF-OS and IIEF-IS domain scores assessed at the time of EF recovery were comparable for patients reaching an IIEF-EF of 22-25 and for patients scoring postoperatively ≥ 26 (8.1, 8.1, and 10.6, 11.4; all P ≥ 0.3). However, mean IIEF-OS and IIEF-IS domain scores of these patients were significantly higher as compared to patients reaching an IIEF-EF domain score < 22 (6.3 and 8.4, respectively; all P ≤ 0.006). Similar results were achieved considering only those patients (group 3) who had complete EF recovery after surgery.
CONCLUSIONS: We demonstrated that in preoperatively fully potent patients treated with BNSRP a lower satisfaction is expected when an IIEF-EF cut-off of 17 is used. Conversely, no difference was found using a cut-off of 22 or 26. Therefore, our results support that a cut-off of IIEF-EF ≥ 22 might represent a reliable score for defining EF recovery after BNSRP.
© 2011 International Society for Sexual Medicine.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21269392     DOI: 10.1111/j.1743-6109.2010.02179.x

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  13 in total

1.  A randomized trial of internet-based versus traditional sexual counseling for couples after localized prostate cancer treatment.

Authors:  Leslie R Schover; Andrea L Canada; Ying Yuan; Dawen Sui; Leah Neese; Rosell Jenkins; Michelle M Rhodes
Journal:  Cancer       Date:  2011-09-26       Impact factor: 6.860

2.  [Oncological and functional results of open intrafascial radical prostatectomy].

Authors:  W Y Khoder; A Buchner; S Siegert; C G Stief; B Schlenker
Journal:  Urologe A       Date:  2011-09       Impact factor: 0.639

3.  Unexpected Long-term Improvements in Urinary and Erectile Function in a Large Cohort of Men with Self-reported Outcomes Following Radical Prostatectomy.

Authors:  Justin K Lee; Melissa Assel; Alan E Thong; Daniel D Sjoberg; John P Mulhall; Jaspreet Sandhu; Andrew J Vickers; Behfar Ehdaie
Journal:  Eur Urol       Date:  2015-08-17       Impact factor: 20.096

4.  Preoperative erectile function is the only predictor of the use of a high number of phosphodiesterase type-5 inhibitors after bilateral nerve-sparing radical prostatectomy.

Authors:  G Gandaglia; A Gallina; N Suardi; F Abdollah; N Passoni; M Bianchi; E Zaffuto; A Nini; D Vizziello; A Salonia; F Montorsi; A Briganti
Journal:  Int J Impot Res       Date:  2014-05-01       Impact factor: 2.896

5.  Non-surgically related causes of erectile dysfunction after bilateral nerve-sparing radical prostatectomy.

Authors:  G Gandaglia; G Lista; N Fossati; N Suardi; A Gallina; M Moschini; L Bianchi; M S Rossi; R Schiavina; S F Shariat; A Salonia; F Montorsi; A Briganti
Journal:  Prostate Cancer Prostatic Dis       Date:  2016-02-09       Impact factor: 5.554

6.  Exploring the Optimal Erectile Function Domain Score Cutoff That Defines Sexual Satisfaction After Radical Prostatectomy.

Authors:  Jean E Terrier; John P Mulhall; Christian J Nelson
Journal:  J Sex Med       Date:  2017-06       Impact factor: 3.802

7.  On the Relationship Between Erectile Function and Sexual Distress in Men with Prostate Cancer.

Authors:  Lauren M Walker; Pablo Santos-Iglesias
Journal:  Arch Sex Behav       Date:  2020-02-18

8.  Exploratory Decision-Tree Modeling of Data from the Randomized REACTT Trial of Tadalafil Versus Placebo to Predict Recovery of Erectile Function After Bilateral Nerve-Sparing Radical Prostatectomy.

Authors:  Francesco Montorsi; Matthias Oelke; Carsten Henneges; Gerald Brock; Andrea Salonia; Gianluca d'Anzeo; Andrea Rossi; John P Mulhall; Hartwig Büttner
Journal:  Eur Urol       Date:  2016-03-03       Impact factor: 20.096

9.  Couple Counseling and Pelvic Floor Muscle Training for Men Operated for Prostate Cancer and for Their Female Partners: Results From the Randomized ProCan Trial.

Authors:  Randi V Karlsen; Pernille E Bidstrup; Annamaria Giraldi; Helle Hvarness; Per Bagi; Susanne Vahr Lauridsen; Vanna Albieri; Marie Frederiksen; Eva Krause; Ulla Due; Christoffer Johansen
Journal:  Sex Med       Date:  2021-06-03       Impact factor: 2.491

Review 10.  Prevention and management of post prostatectomy erectile dysfunction.

Authors:  Andrea Salonia; Giulia Castagna; Paolo Capogrosso; Fabio Castiglione; Alberto Briganti; Francesco Montorsi
Journal:  Transl Androl Urol       Date:  2015-08
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.