Literature DB >> 21256250

Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases.

Eyal Ben-Ami1, Sonia Berrih-Aknin, Ariel Miller.   

Abstract

Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent progenitor cells which can be isolated from various human adult tissues. In recent years, MSCs have been shown to possess broad immunoregulatory capabilities, modulating both adaptive and innate immunity. This review discusses the documented immunomodulatory capabilities of the MSCs, the possible mechanisms underlying these functions and presents the potential of using this stem cell-based approach as an immunomodulatory tool for the treatment of autoimmune diseases.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 21256250     DOI： 10.1016/j.autrev.2011.01.005

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN： 1568-9972            Impact factor:   9.754


  67 in total

1.  Post injury changes in the properties of mesenchymal stem cells derived from human anterior cruciate ligaments.

Authors:  Shuya Nohmi; Yuji Yamamoto; Hiroki Mizukami; Yasuyuki Ishibashi; Eiichi Tsuda; Keiichiro Maniwa; Soroku Yagihashi; Shigeru Motomura; Satoshi Toh; Ken-Ichi Furukawa
Journal:  Int Orthop       Date:  2012-07       Impact factor: 3.075

2.  The modulation of canine mesenchymal stem cells by nano-topographic cues.

Authors:  Joshua A Wood; Irene Ly; Dori L Borjesson; Paul F Nealey; Paul Russell; Christopher J Murphy
Journal:  Exp Cell Res       Date:  2012-07-04       Impact factor: 3.905

3.  Preconditioned mesenchymal stem cells treat myasthenia gravis in a humanized preclinical model.

Authors:  Muriel Sudres; Marie Maurer; Marieke Robinet; Jacky Bismuth; Frédérique Truffault; Diane Girard; Nadine Dragin; Mohamed Attia; Elie Fadel; Nicola Santelmo; Camille Sicsic; Talma Brenner; Sonia Berrih-Aknin
Journal:  JCI Insight       Date:  2017-04-06

Review 4.  Secretion of immunoregulatory cytokines by mesenchymal stem cells.

Authors:  Dobroslav Kyurkchiev; Ivan Bochev; Ekaterina Ivanova-Todorova; Milena Mourdjeva; Tsvetelina Oreshkova; Kalina Belemezova; Stanimir Kyurkchiev
Journal:  World J Stem Cells       Date:  2014-11-26       Impact factor: 5.326

5.  Direct head-to-head comparison of cationic liposome-mediated gene delivery to mesenchymal stem/stromal cells of different human sources: a comprehensive study.

Authors:  Joana S Boura; Francisco Dos Santos; Jeffrey M Gimble; Carla M P Cardoso; Catarina Madeira; Joaquim M S Cabral; Cláudia Lobato da Silva
Journal:  Hum Gene Ther Methods       Date:  2013-02       Impact factor: 2.396

Review 6.  Medical therapies with adult stem/progenitor cells (MSCs): a backward journey from dramatic results in vivo to the cellular and molecular explanations.

Authors:  Darwin J Prockop; Joo Youn Oh
Journal:  J Cell Biochem       Date:  2012-05       Impact factor: 4.429

7.  Serum and xeno-free, chemically defined, no-plate-coating-based culture system for mesenchymal stromal cells from the umbilical cord.

Authors:  Xiaoyun Wu; Huiyan Kang; Xuemin Liu; Jin Gao; Kuijun Zhao; Zhijie Ma
Journal:  Cell Prolif       Date:  2016-08-04       Impact factor: 6.831

8.  Three-Dimensional Spheroid Formation of Cryopreserved Human Dental Follicle-Derived Stem Cells Enhances Pluripotency and Osteogenic Induction Properties.

Authors:  Hyo-Jung Kim; Iel-Yong Sung; Yeong-Cheol Cho; Min-Su Kang; Gyu-Jin Rho; June-Ho Byun; Won-Uk Park; Myeong-Gyun Son; Bong-Wook Park; Hyeon-Jeong Lee; Young-Hoon Kang
Journal:  Tissue Eng Regen Med       Date:  2019-09-12       Impact factor: 4.169

9.  Gene therapy with mesenchymal stem cells expressing IFN-ß ameliorates neuroinflammation in experimental models of multiple sclerosis.

Authors:  C Marin-Bañasco; K Benabdellah; C Melero-Jerez; B Oliver; M J Pinto-Medel; I Hurtado-Guerrero; F de Castro; D Clemente; O Fernández; F Martin; L Leyva; M Suardíaz
Journal:  Br J Pharmacol       Date:  2017-01-12       Impact factor: 8.739

Review 10.  Adipose-Derived Mesenchymal Stem Cells in Autoimmune Disorders: State of the Art and Perspectives for Systemic Sclerosis.

Authors:  Alexandre T J Maria; Marie Maumus; Alain Le Quellec; Christian Jorgensen; Danièle Noël; Philippe Guilpain
Journal:  Clin Rev Allergy Immunol       Date:  2017-04       Impact factor: 8.667
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