Literature DB >> 21251823

Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents.

Steven A Rogers1, Erick A Lindsey, Daniel C Whitehead, Trey Mullikin, Christian Melander.   

Abstract

The successful marriage of structural features from our 2-aminoimidazole and menthyl carbamate classes of anti-biofilm agents has resulted in the development of a novel hybrid scaffold of biofilm modulators. The compounds were evaluated against a panel of four bacterial strains for anti-biofilm and anti-microbial activity.
Copyright © 2010 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21251823     DOI： 10.1016/j.bmcl.2010.12.057

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

1.  2-Aminopyrimidine as a novel scaffold for biofilm modulation.

Authors:  Erick A Lindsey; Roberta J Worthington; Cristina Alcaraz; Christian Melander
Journal:  Org Biomol Chem       Date:  2012-02-02       Impact factor: 3.876

2.  Using Small-Molecule Adjuvants to Repurpose Azithromycin for Use against Pseudomonas aeruginosa.

Authors:  Veronica B Hubble; Brittany A Hubbard; Bradley M Minrovic; Roberta J Melander; Christian Melander
Journal:  ACS Infect Dis       Date:  2018-11-29       Impact factor: 5.084

Review 3.  Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections.

Authors:  Yu-Xuan Ma; Chen-Yu Wang; Yuan-Yuan Li; Jing Li; Qian-Qian Wan; Ji-Hua Chen; Franklin R Tay; Li-Na Niu
Journal:  Adv Sci (Weinh)       Date:  2019-12-05       Impact factor: 16.806

4.  Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms.

Authors:  Cynthia Bunders; John Cavanagh; Christian Melander
Journal:  Org Biomol Chem       Date:  2011-06-15       Impact factor: 3.876

5.  Evaluation of ethyl N-(2-phenethyl) carbamate analogues as biofilm inhibitors of methicillin resistant Staphylococcus aureus.

Authors:  Matthew D Stephens; Nisakorn Yodsanit; Christian Melander
Journal:  Org Biomol Chem       Date:  2016-07-12       Impact factor: 3.876

Review 6.  High-Throughput Approaches for the Identification of Pseudomonas aeruginosa Antivirulents.

Authors:  Donghoon Kang; Liyang Zhang; Natalia V Kirienko
Journal:  mBio       Date:  2021-05-04       Impact factor: 7.867

Review 7.  Inhibition of Virulence Factors and Biofilm Formation of Acinetobacter Baumannii by Naturally-derived and Synthetic Drugs.

Authors:  Nilushi Indika Bamunuarachchi; Fazlurrahman Khan; Young-Mog Kim
Journal:  Curr Drug Targets       Date:  2021       Impact factor: 2.937

8.  Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues.

Authors:  Nace Zidar; Sofia Montalvão; Žiga Hodnik; Dorota A Nawrot; Aleš Žula; Janez Ilaš; Danijel Kikelj; Päivi Tammela; Lucija Peterlin Mašič
Journal:  Mar Drugs       Date:  2014-02-14       Impact factor: 5.118
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.