| Literature DB >> 21247215 |
Paul A Clarke1, Soraia Santos, Nimesh Mistry, Laurence Burroughs, Alexander C Humphries.
Abstract
The synthesis of the C1-C19 bis-pyran unit of phorboxazole B has been achieved. The key pyran rings were constructed by means of an asymmetric Maitland-Japp reaction and a second Maitland-Japp resolution/cyclization reaction. The longest linear sequence was 14 steps, and the C1-C19 bis-pyran unit was formed in an impressive 10.4% yield.Entities:
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Year: 2011 PMID： 21247215 DOI： 10.1021/ol102860r
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005