Literature DB >> 24218144

A tandem isomerization/prins strategy: iridium(III)/Brønsted acid cooperative catalysis.

Vince M Lombardo1, Christopher D Thomas, Karl A Scheidt.   

Abstract

Working together: A mild and efficient isomerization/protonation sequence generates pyran-fused indoles by cooperative catalysis between cationic iridium(III) and Bi(OTf)3 . Three distinct cyclization manifolds lead to the corresponding bioactive scaffolds in good yields. In addition, N-substituted indoles can be synthesized enantioselectively in the presence of a chiral phosphate.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  bismuth; cooperative catalysis; cyclization; heterocycles; synthetic methods

Mesh：

Substances：

Year:  2013        PMID： 24218144      PMCID： PMC3905988          DOI： 10.1002/anie.201306462

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  65 in total

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  2 in total

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Journal:  Angew Chem Int Ed Engl       Date:  2018-11-27       Impact factor: 15.336

Review 2.  Recent Advances in the Prins Reaction.

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  2 in total

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