PURPOSE: The human nucleus accumbens (NA), which belongs to the basal ganglia of the brain, is the main part of the ventral striatum. The purpose of our clinically oriented anatomical-radiologic study was to provide anatomical and imaging data of the human NA, primarily useful to neurosurgeons. METHODS: For our imaging study, we used cerebral magnetic resonance images (MRIs) from 26 neurosurgical patients (52 NAs). The material for our anatomic study consisted of 32 cerebral hemispheres (32 NAs) from 18 normal human brains which we have in our department (Department of Anatomy) from cadaver donors. We measured and analyzed the dimensions of the NA at specific clinically important transverse, coronal and sagittal levels. RESULTS: The human NA suffers from age-related but no side- or sex-related morphometric changes. In surgically important stereotactic levels this nucleus is easily identifiable on MRIs. CONCLUSIONS: We present an anatomic guide of the NA from carefully measured data of our extensive and combined study and we hope that our work will be really helpful to neuroscientists interested in the NA.
PURPOSE: The human nucleus accumbens (NA), which belongs to the basal ganglia of the brain, is the main part of the ventral striatum. The purpose of our clinically oriented anatomical-radiologic study was to provide anatomical and imaging data of the human NA, primarily useful to neurosurgeons. METHODS: For our imaging study, we used cerebral magnetic resonance images (MRIs) from 26 neurosurgical patients (52 NAs). The material for our anatomic study consisted of 32 cerebral hemispheres (32 NAs) from 18 normal human brains which we have in our department (Department of Anatomy) from cadaver donors. We measured and analyzed the dimensions of the NA at specific clinically important transverse, coronal and sagittal levels. RESULTS: The human NA suffers from age-related but no side- or sex-related morphometric changes. In surgically important stereotactic levels this nucleus is easily identifiable on MRIs. CONCLUSIONS: We present an anatomic guide of the NA from carefully measured data of our extensive and combined study and we hope that our work will be really helpful to neuroscientists interested in the NA.
Authors: N A Shapira; M S Okun; D Wint; K D Foote; J A Byars; D Bowers; U S Springer; P J Lang; B D Greenberg; S N Haber; W K Goodman Journal: J Neurol Neurosurg Psychiatry Date: 2006-03 Impact factor: 10.154
Authors: Donald A Malone; Darin D Dougherty; Ali R Rezai; Linda L Carpenter; Gerhard M Friehs; Emad N Eskandar; Scott L Rauch; Steven A Rasmussen; Andre G Machado; Cynthia S Kubu; Audrey R Tyrka; Lawrence H Price; Paul H Stypulkowski; Jonathon E Giftakis; Mark T Rise; Paul F Malloy; Stephen P Salloway; Benjamin D Greenberg Journal: Biol Psychiatry Date: 2008-10-08 Impact factor: 13.382
Authors: Thomas E Schlaepfer; Michael X Cohen; Caroline Frick; Markus Kosel; Daniela Brodesser; Nikolai Axmacher; Alexius Young Joe; Martina Kreft; Doris Lenartz; Volker Sturm Journal: Neuropsychopharmacology Date: 2007-04-11 Impact factor: 7.853
Authors: Charles B Mikell; Guy M McKhann; Solomon Segal; Robert A McGovern; Matthew B Wallenstein; Holly Moore Journal: Stereotact Funct Neurosurg Date: 2009-06-26 Impact factor: 1.875