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Literature DB >> 17878197

Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications?

Jens Kuhn¹, Doris Lenartz, Wolfgang Huff, SunHee Lee, Athanasios Koulousakis, Joachim Klosterkoetter, Volker Sturm.

Abstract

Chronic consumption of alcohol represents one of the greatest health and socioeconomic problems worldwide. We report on a 54-year-old patient with a severe anxiety disorder and secondary depressive disorder in whom bilateral deep brain stimulation (DBS) of the nucleus accumbens was carried out. Despite the absence of desired improvement in his primary disorder, we observed a remarkable although not primarily intended alleviation of the patient's comorbid alcohol dependency. Our case report demonstrates the extremely effective treatment of alcohol dependency by means of DBS of the nucleus accumbens and may reveal new prospects in overcoming therapy resistance in dependencies in general.

Entities: Chemical Disease Species

Mesh：

Year: 2007 PMID： 17878197 PMCID： PMC2117573 DOI： 10.1136/jnnp.2006.113092

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

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