Literature DB >> 7704301

Evidence for two neurochemical divisions in the human nucleus accumbens.

P Voorn1, L S Brady, A Schotte, H W Berendse, E K Richfield.   

Abstract

The neurochemical anatomy of the human nucleus accumbens was studied by comparing the distributional patterns of [3H]DAMGE (mu opioid receptor), [3H]bremazocine (kappa opioid receptor), [3H]SCH-23390 (D1-like dopamine receptor), [3H]7-OH-DPAT (D3 dopamine receptor) binding, preproenkephalin mRNA and acetylcholinesterase activity in sections of post mortem human striatum. Our results demonstrate the presence of at least two neurochemically distinct divisions within the human nucleus accumbens, which may be homologous to the 'shell' and 'core' divisions of the nucleus as found in the rat.

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Year:  1994        PMID： 7704301     DOI： 10.1111/j.1460-9568.1994.tb00582.x

Source DB:  PubMed          Journal:  Eur J Neurosci        ISSN： 0953-816X            Impact factor:   3.386


  11 in total

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3.  Anatomy of the human nucleus accumbens: a combined morphometric study.

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5.  Connectivity-based parcellation of the nucleus accumbens into core and shell portions for stereotactic target localization and alterations in each NAc subdivision in mTLE patients.

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6.  Volumetric data of normal nucleus accumbens from magnetic resonance imaging scans.

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7.  Dendritic distributions of dopamine D1 receptors in the rat nucleus accumbens are synergistically affected by startle-evoking auditory stimulation and apomorphine.

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8.  Electrophysiological evidence of mediolateral functional dichotomy in the rat accumbens during cocaine self-administration: tonic firing patterns.

Authors:  Anthony T Fabbricatore; Udi E Ghitza; Volodymyr F Prokopenko; Mark O West
Journal:  Eur J Neurosci       Date:  2009-12-10       Impact factor: 3.386

9.  Multimodal characterization of the human nucleus accumbens.

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10.  Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by D-amphetamine.

Authors:  J A Parkinson; M C Olmstead; L H Burns; T W Robbins; B J Everitt
Journal:  J Neurosci       Date:  1999-03-15       Impact factor: 6.167
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