Literature DB >> 21182258

Tirucallane triterpenoids from Cornus walteri.

Ki Hyun Kim1, Sang Un Choi, Young Choong Kim, Kang Ro Lee.   

Abstract

Twelve new tirucallane triterpenoids, named cornusalterins A-L (1-12), and two known tirucallane triterpenoids, deoxyflindissone (13) and (-)-leucophyllone (14), were isolated from a MeOH extract of stems and stem bark of Cornus walteri. The structures of the new compounds were determined by spectroscopic methods, including 1D and 2D NMR analyses. Compounds 12 and 13, possessing a tetrahydrofuran ring in the side chain, exhibited significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.

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Year:  2010        PMID： 21182258     DOI： 10.1021/np100660v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

1.  Three new fatty acid esters from the mushroom Boletus pseudocalopus.

Authors:  Ki Hyun Kim; Sang Un Choi; Kang Ro Lee
Journal:  Lipids       Date:  2012-01-24       Impact factor: 1.880

Review 2.  Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance.

Authors:  Tanya Biswas; Upendra N Dwivedi
Journal:  Protoplasma       Date:  2019-07-11       Impact factor: 3.356

3.  Chakyunglupulins A and B, two novel 4,8,8-trimethylcyclooct-2-enone derivatives from Barleria lupulina.

Authors:  Ki Hyun Kim; Jon Clardy; Donald Senger; Shugeng Cao
Journal:  Tetrahedron Lett       Date:  2015-05-20       Impact factor: 2.415

4.  Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis.

Authors:  Dahae Lee; Seoung Rak Lee; Ki Sung Kang; Yuri Ko; Changhyun Pang; Noriko Yamabe; Ki Hyun Kim
Journal:  Biomolecules       Date:  2019-07-03

5.  Benzyl salicylate from the stems and stem barks of Cornus walteri as a nephroprotective agent against cisplatin-induced apoptotic cell death in LLC-PK1 cells.

Authors:  Dahae Lee; Seoung Rak Lee; Ki Sung Kang; Ki Hyun Kim
Journal:  RSC Adv       Date:  2020-02-05       Impact factor: 4.036

6.  Tirucallane Triterpenoids from the Stems and Stem Bark of Cornus walteri that Control Adipocyte and Osteoblast Differentiations.

Authors:  Seoung Rak Lee; Eunyong Choi; Se Hun Jeon; Xue Yan Zhi; Jae Sik Yu; Seon-Hee Kim; Jeongmi Lee; Ki-Moon Park; Ki Hyun Kim
Journal:  Molecules       Date:  2018-10-23       Impact factor: 4.411

7.  Identification of Bioactive Natural Product from the Stems and Stem Barks of Cornus walteri: Benzyl Salicylate Shows Potential Anti-Inflammatory Activity in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages.

Authors:  Dahae Lee; Akida Alishir; Tae Su Jang; Ki Hyun Kim
Journal:  Pharmaceutics       Date:  2021-03-25       Impact factor: 6.321
  7 in total

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