| Literature DB >> 22271425 |
Ki Hyun Kim1, Sang Un Choi, Kang Ro Lee.
Abstract
A bioassay-guided fractionation and chemical investigation of a MeOH extract of the Korean wild mushroom Boletus pseudocalopus resulted in the identification of three new fatty acid esters, named calopusins A-C (1-3), along with two known fatty acid methyl esters (4-5). These new compounds are structurally unique fatty acid esters with a 2,3-butanediol moiety. Their structures were elucidated through 1D- and 2D-NMR spectroscopic data and GC-MS analysis as well as a modified Mosher's method. The new compounds 1-3 showed significant inhibitory activity against the proliferation of the tested cancer cell lines with IC(50) values in the range 2.77-12.51 μM.Entities:
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Year: 2012 PMID： 22271425 DOI： 10.1007/s11745-012-3657-2
Source DB: PubMed Journal: Lipids ISSN： 0024-4201 Impact factor: 1.880