Literature DB >> 21179306

Mediastinitis in pediatric cardiac surgery: Prevention, diagnosis and treatment.

Yves Durandy1.   

Abstract

In spite of advances in the management of mediastinitis following sternotomy, mediastinitis is still associated with significant morbidity. The prognosis is much better in pediatric surgery compared to adult surgery, but the prolonged hospital stays with intravenous therapy and frequent required dressing changes that occur with several therapeutic approaches are poorly tolerated. Prevention includes nasal decontamination, skin preparation, antibioprophylaxis and air filtration in the operating theater. The expertise of the surgical team is an additional factor that is difficult to assess precisely. Diagnosis is often very simple, being made on the basis of a septic state with wound modification, while retrosternal puncture and CT scan are rarely useful. Treatment of mediastinitis following sternotomy is always a combination of surgical debridement and antibiotic therapy. Continued use of numerous surgical techniques demonstrates that there is no consensus and the best treatment has yet to be determined. However, we suggest that a primary sternal closure is the best surgical option for pediatric patients. We propose a simple technique with high-vacuum Redon's catheter drainage that allows early mobilization and short term antibiotherapy, which thus decreases physiological and psychological trauma for patients and families. We have demonstrated the efficiency of this technique, which is also cost-effective by decreasing intensive care and hospital stay durations, in a large group of patients.

Entities:  

Keywords:  Mediastinal infection; Mediastinitis drainage; Pediatric cardiac surgery; Prevention of mediastinitis; Staphylococcus post cardiac surgery infection; Treatment of mediastinitis

Year:  2010        PMID: 21179306      PMCID: PMC3006475          DOI: 10.4330/wjc.v2.i11.391

Source DB:  PubMed          Journal:  World J Cardiol


  90 in total

1.  Computed tomography of the sternum and mediastinum after median sternotomy.

Authors:  C Y Bitkover; K Cederlund; B Aberg; J Vaage
Journal:  Ann Thorac Surg       Date:  1999-09       Impact factor: 4.330

2.  A foreign body reaction to Surgicel mimicking an abscess following cardiac surgery.

Authors:  Mohamed F Ibrahim; Christopher Aps; Christopher P Young
Journal:  Eur J Cardiothorac Surg       Date:  2002-09       Impact factor: 4.191

Review 3.  Meta-analysis of preoperative antiseptic bathing in the prevention of surgical site infection.

Authors:  J Webster; S Osborne
Journal:  Br J Surg       Date:  2006-11       Impact factor: 6.939

4.  Hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery: assessment using magnetic resonance imaging.

Authors:  Rainer Petzina; Martin Ugander; Lotta Gustafsson; Henrik Engblom; Johan Sjögren; Roland Hetzer; Richard Ingemansson; Håkan Arheden; Malin Malmsjö
Journal:  J Thorac Cardiovasc Surg       Date:  2007-05       Impact factor: 5.209

5.  An imbalance in T-helper cell subsets alters immune response after cardiac surgery.

Authors:  A Markewitz; E Faist; S Lang; L Hültner; C Weinhold; B Reichart
Journal:  Eur J Cardiothorac Surg       Date:  1996       Impact factor: 4.191

6.  Mediastinal infection after cardiac operation. A simple closed technique.

Authors:  Y Durandy; A Batisse; P Bourel; A Dibie; G Lemoine; Y Lecompte
Journal:  J Thorac Cardiovasc Surg       Date:  1989-02       Impact factor: 5.209

7.  Risk factors for sternal wound and other infections in pediatric cardiac surgery patients.

Authors:  P A Mehta; C K Cunningham; C B Colella; G Alferis; L B Weiner
Journal:  Pediatr Infect Dis J       Date:  2000-10       Impact factor: 2.129

8.  Intranasal mupirocin reduces sternal wound infection after open heart surgery in diabetics and nondiabetics.

Authors:  G E Cimochowski; M D Harostock; R Brown; M Bernardi; N Alonzo; K Coyle
Journal:  Ann Thorac Surg       Date:  2001-05       Impact factor: 4.330

9.  Multiply beta-lactam resistant Enterobacter cloacae infections linked to the environmental flora in a unit for cardiothoracic and vascular surgery.

Authors:  B M Andersen; D Sørlie; R Hotvedt; S M Almdahl; K Olafsen; R George; A Gilfillian
Journal:  Scand J Infect Dis       Date:  1989

10.  Effects of cardiopulmonary bypass circuit reduction and residual volume salvage on allogeneic transfusion requirements in infants undergoing cardiac surgery.

Authors:  Hanna D Golab; Johanna J M Takkenberg; Gerri L van Gerner-Weelink; Marianne J Wijers; Thierry V Scohy; Peter L de Jong; Ad J J C Bogers
Journal:  Interact Cardiovasc Thorac Surg       Date:  2007-03-26
View more
  3 in total

1.  Successful Salvage of an Extracardiac Fontan in the Setting of Purulent Mediastinitis using Antibiotic-Impregnated Beads.

Authors:  Matthew T Coghill; Gonzalo A Wallis; Paul M Kirshbom; Thomas S Maxey
Journal:  J Pediatr Intensive Care       Date:  2018-02-06

2.  Enterococcus faecium Mediastinitis Complicated by Disseminated Candida parapsilosis Infection after Congenital Heart Surgery in a 4-Week-Old Baby.

Authors:  Hanna Renk; Felix Neunhoeffer; Florian Hölzl; Michael Hofbeck; Matthias Kumpf
Journal:  Case Rep Infect Dis       Date:  2015-10-28

3.  Acute mediastinitis in children: a nine-year experience.

Authors:  Ahmad Khaleghnejad Tabari; Alireza Mirshemirani; Mohsen Rouzrokh; Laili Mohajerzadeh; Nasibeh Khaleghnejad Tabari; Parand Ghaffari
Journal:  Tanaffos       Date:  2013
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.